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NCT05547880 · ClinicalTrials.gov registry record
CNS Correlates of Extended Sleep Restriction
A clinical trial, sponsored by Walter Reed Army Institute of Research (WRAIR).
- Completed
- Registry status
- 13
- Enrollment target
NCT05547880: Completed study, sponsored by Walter Reed Army Institute of Research (WRAIR).
NCT05547880 is a clinical trial that has completed, run by Walter Reed Army Institute of Research (WRAIR). The registered enrollment target is 13 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05547880 has completed, sponsored by Walter Reed Army Institute of Research (WRAIR).
- COMPLETED
- Registry status
- 13 participants
- Enrollment target
Study Summary
Chronic sleep restriction is ubiquitous in both the general population and the military. The deleterious effects of sleep loss on human alertness and cognitive performance have been documented in numerous studies dating back to the nineteenth century. Over the past decade, evidence has emerged indicating that chronic sleep restriction may also precipitate deleterious, long lasting neuropathological changes in the brain. The purpose of this study is to determine neuropathological effects of sleep restriction and identify physiological mechanisms that correlate with sleep loss-induced performance impairment.
Primary Outcome
Positron Emission Tomography (PET) is the brain imaging method and \[11C\]ER176 is the PET radioligand providing an index of neuroinflammation
Interventions
- DRUG [11C]ER176
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2023-05-23 |
| Est. Completion | 2025-03-15 |
What the finished NCT05547880 record still lists
NCT05547880 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 13 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which [11C]ER176 is the first listed.
NCT05547880 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05547880 about?
NCT05547880 is a clinical study titled "CNS Correlates of Extended Sleep Restriction". Chronic sleep restriction is ubiquitous in both the general population and the military. The deleterious effects of sleep loss on human alertness and cognitive performance have been documented in numerous studies dating back to the nineteenth century. Over the past decade, evidence has emerged indic...
What is the current status of trial NCT05547880?
This trial is currently completed. The enrollment target is 13 participants. The study started on 2023-05-23. Estimated completion is 2025-03-15.
What interventions are being tested in trial NCT05547880?
The interventions under investigation include: [11C]ER176 (DRUG).
Who is sponsoring clinical trial NCT05547880?
This trial is sponsored by Walter Reed Army Institute of Research (WRAIR), which has 12 total clinical trials registered on ClinicalTrials.gov.
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