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NCT05546827 · ClinicalTrials.gov registry record · Phase 2
Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma
A Phase 2 study of Sinonasal Melanoma and Anorectal Melanoma, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05546827: Recruiting Phase 2 study of Sinonasal Melanoma and Anorectal Melanoma, sponsored by M.D. Anderson Cancer Center.
NCT05546827 is a Phase 2 study of Sinonasal Melanoma and Anorectal Melanoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05546827, a Phase 2 study of Sinonasal Melanoma and Anorectal Melanoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical research study is to learn if pre-operative radiation therapy after starting immune checkpoint inhibition can help patients with sinonasal or anorectal melanoma have better outcomes
Conditions Studied
Interventions
- PROCEDURE Surgical resection
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2022-09-23 |
| Est. Completion | 2028-07-31 |
| Phase | Phase 2 |
What NCT05546827 shows while recruiting
NCT05546827 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 2 conditions, with Sinonasal Melanoma appearing as the primary indexed condition, and to 1 intervention - of which Surgical resection is the first listed.
NCT05546827 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05546827 about?
NCT05546827 is a clinical study titled "Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal Melanoma". The goal of this clinical research study is to learn if pre-operative radiation therapy after starting immune checkpoint inhibition can help patients with sinonasal or anorectal melanoma have better outcomes
What is the current status of trial NCT05546827?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2022-09-23. Estimated completion is 2028-07-31.
What conditions does trial NCT05546827 study?
This clinical trial studies the following conditions: Sinonasal Melanoma, Anorectal Melanoma.
What interventions are being tested in trial NCT05546827?
The interventions under investigation include: Surgical resection (PROCEDURE).
Who is sponsoring clinical trial NCT05546827?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05546827 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05546827's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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