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NCT05542238 · ClinicalTrials.gov registry record · NA
The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
A NA study, sponsored by State University of New York at Buffalo.
- Terminated
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT05542238 is a NA study that was terminated before completion, run by State University of New York at Buffalo. The registered enrollment target is 6 participants.
The verdict
NCT05542238, a NA study, was terminated before completion, sponsored by State University of New York at Buffalo.
- TERMINATED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
The aims of this proposal are to: 1) investigate whether individuals with spinal cord injury (SCI) demonstrate cardiac autonomic, cerebrovascular, and cognitive dysfunctions compared to non-injured age- and sex-matched controls in the following conditions: supine rest and head-up tilt/face-cooling test; 2) examine if autonomic completeness/ incompleteness, physical activity, and psychological distress are predictors for dysfunctions during supine rest and head-up tilt/face cooling conditions in SCI individuals; 3) examine if one bout of moderate-intensity aerobic exercise temporarily improves cardiac autonomic and cerebrovascular functions and thereby improves cognition when in supine rest and head- up tilt/face cooling conditions. The study will include an initial visit and an experimental visit to our lab. Three groups of participants will be included in this study: Group 1, SCI with acute exercise; group 2, SCI with rest-control; and group 3, age- and sex-matched non-injured individuals. Cardiovascular variables, such as heart rate variability, blood pressure variability, and cerebrovascular variables, such as cerebral blood flow velocity and oxygenated hemoglobin, and cognitive performance will be examined. The investigator hypothesizes that individuals with SCI will have impaired cardiac autonomic, cerebrovascular, and cognitive functions compared to the non-injured controls, and an acute exercise can improve those functions. Autonomic completeness/incompleteness, physical activity, and psychological distress are significant factors that predict cardiac autonomic, cerebrovascular, and cognitive functions in individuals with SCI.
Interventions
- BEHAVIORAL One bout of moderate-intensity sub-maximal aerobic exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2022-09-06 |
| Est. Completion | 2024-12-18 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05542238
The ClinicalTrials.gov registry entry for NCT05542238 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is State University of New York at Buffalo, which has 243 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which One bout of moderate-intensity sub-maximal aerobic exercise is the first listed.
NCT05542238 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05542238 about?
NCT05542238 is a clinical study titled "The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury". The aims of this proposal are to: 1) investigate whether individuals with spinal cord injury (SCI) demonstrate cardiac autonomic, cerebrovascular, and cognitive dysfunctions compared to non-injured age- and sex-matched controls in the following conditions: supine rest and head-up tilt/face-cooling t...
What is the current status of trial NCT05542238?
This trial is currently terminated. It is a NA study. The enrollment target is 6 participants. The study started on 2022-09-06. Estimated completion is 2024-12-18.
What interventions are being tested in trial NCT05542238?
The interventions under investigation include: One bout of moderate-intensity sub-maximal aerobic exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT05542238?
This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.
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