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NCT05524844 · ClinicalTrials.gov registry record
The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE)
A clinical trial of Esophageal Adenocarcinoma and Barrett Esophagus, sponsored by Columbia University.
- Completed
- Registry status
- 54
- Enrollment target
- 2
- Study locations
NCT05524844 is a study of Esophageal Adenocarcinoma and Barrett Esophagus that has completed, run by Columbia University. The registered enrollment target is 54 participants, below the 307-participant average among 43 other Esophageal Adenocarcinoma trials with a reported enrollment target (82% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT05524844, a study of Esophageal Adenocarcinoma and Barrett Esophagus, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 54 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to prospectively collect and analyze clinical data and biospecimens from a cohort of 100 patients without BE (20), with non-dysplastic BE (40), or with BE and high grade dysplasia (HGD) or EAC (40). The investigators will enroll 80 patients scheduled for upper endoscopy for clinical purposes, with a history of histologically confirmed BE (2 cm length); 40 with no history of dysplasia, and 40 with HGD or EAC. The investigators will also enroll 20 non-BE controls undergoing endoscopy for any indication who are on stable dose proton-pump inhibitors (PPI) for the past month. PPI therapy is standard of care for BE patients.
Conditions Studied
Interventions
- OTHER Sample Collection
- OTHER Endoscopy results
- OTHER Dietary questionnaire
Study Locations (2)
New York
- Columbia University Irving Medical Center - New York
- Weill Cornell Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2021-02-09 |
| Est. Completion | 2024-11-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05524844
The ClinicalTrials.gov registry entry for NCT05524844 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 307-participant average among 43 other Esophageal Adenocarcinoma trials with a reported enrollment target (82% lower). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Esophageal Adenocarcinoma appearing as the primary indexed condition, and to 3 interventions - of which Sample Collection is the first listed.
NCT05524844 reports 2 study locations spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05524844 about?
NCT05524844 is a clinical study titled "The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE)". The purpose of this study is to prospectively collect and analyze clinical data and biospecimens from a cohort of 100 patients without BE (20), with non-dysplastic BE (40), or with BE and high grade dysplasia (HGD) or EAC (40). The investigators will enroll 80 patients scheduled for upper endoscopy ...
What is the current status of trial NCT05524844?
This trial is currently completed. The enrollment target is 54 participants. The study started on 2021-02-09. Estimated completion is 2024-11-01.
What conditions does trial NCT05524844 study?
This clinical trial studies the following conditions: Esophageal Adenocarcinoma, Barrett Esophagus.
What interventions are being tested in trial NCT05524844?
The interventions under investigation include: Sample Collection (OTHER), Endoscopy results (OTHER), Dietary questionnaire (OTHER).
Who is sponsoring clinical trial NCT05524844?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05524844 being conducted?
This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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