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NCT05521022 · ClinicalTrials.gov registry record · Phase 1

Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis

A Phase 1 study of Amyloidosis; Systemic, sponsored by Attralus.

Recruiting
Registry status
Phase 1
Development phase
100
Enrollment target
11
Study locations

NCT05521022 is a Phase 1 study of Amyloidosis; Systemic that is actively recruiting participants, run by Attralus. The registered enrollment target is 100 participants. The trial reports 11 study locations across 10 states.

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The verdict

NCT05521022, a Phase 1 study of Amyloidosis; Systemic, is actively recruiting participants, sponsored by Attralus.

RECRUITING
Registry status
Phase 1
Development phase
100 participants
Enrollment target
11
Study locations

Study Summary

This is a multicenter, international, three-part, Phase 1 study designed to evaluate the safety, tolerability, and PK of rising single doses of AT-02 in healthy volunteers and in subjects with systemic amyloidosis and to assess the safety, tolerability, and PK of multiple doses of AT-02 in subjects with systemic amyloidosis.

Conditions Studied

Interventions

  • DRUG AT-02
  • OTHER AT-02 (Placebo)

Study Locations (11)

Queensland

  • Q-Pharm Pty Ltd - Herston
  • Princess Alexandra Hospital - Woolloongabba

Kansas

  • Midwest Heart and Vascular - Overland Park

Maryland

  • Johns Hopkins - Baltimore

Missouri

  • St. Luke's Hospital of Kansas City - Kansas City

Ohio

  • Cleveland Clinic - Cleveland

Oregon

  • OHSU (Oregon Health & Science University) - Portland

Pennsylvania

  • Penn Presbyterian Medical Center - Philadelphia

South Australia

  • Flinders Medical Centre - Bedford Park

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2022-09-01
Est. Completion 2025-03-01
Phase Phase 1

Sponsor

Attralus

4 total trials

What the Registry Record Tells You About NCT05521022

The ClinicalTrials.gov registry entry for NCT05521022 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Attralus, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amyloidosis; Systemic appearing as the primary indexed condition, and to 2 interventions - of which AT-02 is the first listed.

NCT05521022 reports 11 study locations spanning 10 distinct geographic areas - top geographies include Queensland, Kansas, Maryland.

Frequently Asked Questions

What is clinical trial NCT05521022 about?

NCT05521022 is a clinical study titled "Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis". This is a multicenter, international, three-part, Phase 1 study designed to evaluate the safety, tolerability, and PK of rising single doses of AT-02 in healthy volunteers and in subjects with systemic amyloidosis and to assess the safety, tolerability, and PK of multiple doses of AT-02 in subjects ...

What is the current status of trial NCT05521022?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2022-09-01. Estimated completion is 2025-03-01.

What conditions does trial NCT05521022 study?

This clinical trial studies the following conditions: Amyloidosis; Systemic.

What interventions are being tested in trial NCT05521022?

The interventions under investigation include: AT-02 (DRUG), AT-02 (Placebo) (OTHER).

Who is sponsoring clinical trial NCT05521022?

This trial is sponsored by Attralus, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05521022 being conducted?

This trial has 11 study locations across Kansas, Maryland, Missouri, Ohio, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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