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ACTIVE NOT RECRUITING Phase 3

PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial

NCT05511922 · View on ClinicalTrials.gov ↗

Study Summary

This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 (sebetralstat) in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.

Conditions Studied

Interventions

  • DRUG KVD900 600 mg
  • DRUG Drug: KVD900 300 mg

Study Locations (20)

California

  • KalVista Investigative Site — San Diego
  • KalVista Investigative Site — San Diego
  • KalVista Investigative Site — Santa Monica

Colorado

  • KalVista Investigative Site — Centennial
  • KalVista Investigative Site — Colorado Springs

Ohio

  • KalVista Investigative Site — Cincinnati
  • KalVista Investigative Site — Toledo

Arizona

  • KalVista Investigative Site — Scottsdale

Arkansas

  • KalVista Investigative Site — Little Rock

Indiana

  • KalVista Investigative Site — Evansville

Kansas

  • KalVista Investigative Site — Overland Park

Kentucky

  • KalVista Investigative Site — Louisville

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2022-10-24
Est. Completion 2026-06-30
Phase Phase 3

Sponsor

KalVista Pharmaceuticals

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05511922

The ClinicalTrials.gov registry entry for NCT05511922 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is KalVista Pharmaceuticals, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hereditary Angioedema appearing as the primary indexed condition, and to 2 interventions — of which KVD900 600 mg is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05511922 reports 20 study locations spanning 16 distinct geographic areas — top geographies include California, Colorado, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05511922 about?

NCT05511922 is a clinical study titled "PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial". This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 (sebetralstat) in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.

What is the current status of trial NCT05511922?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 11 participants. The study started on 2022-10-24. Estimated completion is 2026-06-30.

What conditions does trial NCT05511922 study?

This clinical trial studies the following conditions: Hereditary Angioedema. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05511922?

The interventions under investigation include: KVD900 600 mg (DRUG), Drug: KVD900 300 mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05511922?

This trial is sponsored by KalVista Pharmaceuticals, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05511922 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial