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NCT05511922 · ClinicalTrials.gov registry record · Phase 3
PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial
A Phase 3 study of Hereditary Angioedema, sponsored by KalVista Pharmaceuticals.
- Active
- Registry status
- Phase 3
- Development phase
- 11
- Enrollment target
- 20
- Study locations
NCT05511922: Active Phase 3 study of Hereditary Angioedema, sponsored by KalVista Pharmaceuticals.
NCT05511922 is a Phase 3 study of Hereditary Angioedema that is active but no longer recruiting, run by KalVista Pharmaceuticals. The registered enrollment target is 11 participants, below the 75-participant average among 14 other Hereditary Angioedema trials with a reported enrollment target (85% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05511922, a Phase 3 study of Hereditary Angioedema, is active but no longer recruiting, sponsored by KalVista Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 11 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 (sebetralstat) in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.
Conditions Studied
Interventions
- DRUG KVD900 600 mg
- DRUG Drug: KVD900 300 mg
Study Locations (20)
California
- KalVista Investigative Site - San Diego
- KalVista Investigative Site - San Diego
- KalVista Investigative Site - Santa Monica
Colorado
- KalVista Investigative Site - Centennial
- KalVista Investigative Site - Colorado Springs
Ohio
- KalVista Investigative Site - Cincinnati
- KalVista Investigative Site - Toledo
Arizona
- KalVista Investigative Site - Scottsdale
Arkansas
- KalVista Investigative Site - Little Rock
Indiana
- KalVista Investigative Site - Evansville
Kansas
- KalVista Investigative Site - Overland Park
Kentucky
- KalVista Investigative Site - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2022-10-24 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 3 |
What the registry record for NCT05511922 still lists
NCT05511922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 75-participant average among 14 other Hereditary Angioedema trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Hereditary Angioedema appearing as the primary indexed condition, and to 2 interventions - of which KVD900 600 mg is the first listed.
NCT05511922 names 20 study sites across 16 states, led by California, Colorado, Ohio.
Frequently Asked Questions
What is clinical trial NCT05511922 about?
NCT05511922 is a clinical study titled "PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial". This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 (sebetralstat) in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.
What is the current status of trial NCT05511922?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 11 participants. The study started on 2022-10-24. Estimated completion is 2026-06-30.
What conditions does trial NCT05511922 study?
This clinical trial studies the following conditions: Hereditary Angioedema.
What interventions are being tested in trial NCT05511922?
The interventions under investigation include: KVD900 600 mg (DRUG), Drug: KVD900 300 mg (DRUG).
Who is sponsoring clinical trial NCT05511922?
This trial is sponsored by KalVista Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05511922 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hereditary Angioedema
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05511922's enrollment target sits among peer trials
11 15th of 14 the lowest of 14 other Hereditary Angioedema trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hereditary Angioedema trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
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-
An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
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A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)
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HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE)
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-
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OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE)
COMPLETED · Phase 3
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