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NCT05507216 · ClinicalTrials.gov registry record · Phase 3

ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

A Phase 3 study, sponsored by Abivax S.A..

Completed
Registry status
Phase 3
Development phase
636
Enrollment target

NCT05507216 is a Phase 3 study that has completed, run by Abivax S.A.. The registered enrollment target is 636 participants.

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The verdict

NCT05507216, a Phase 3 study, has completed, sponsored by Abivax S.A..

COMPLETED
Registry status
Phase 3
Development phase
636 participants
Enrollment target

Study Summary

This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrins, anti-IL-23), and/or S1P receptor modulators, and/or JAK inhibitors\].

Interventions

  • DRUG Placebo
  • DRUG ABX464

Trial Details

FieldValue
Enrollment Target 636 participants
Start Date 2022-12-21
Est. Completion 2025-07-15
Phase Phase 3

Sponsor

Abivax S.A.

6 total trials

What the Registry Record Tells You About NCT05507216

The ClinicalTrials.gov registry entry for NCT05507216 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 636 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abivax S.A., which has 6 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05507216 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05507216 about?

NCT05507216 is a clinical study titled "ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2". This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an into...

What is the current status of trial NCT05507216?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 636 participants. The study started on 2022-12-21. Estimated completion is 2025-07-15.

What interventions are being tested in trial NCT05507216?

The interventions under investigation include: Placebo (DRUG), ABX464 (DRUG).

Who is sponsoring clinical trial NCT05507216?

This trial is sponsored by Abivax S.A., which has 6 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.