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NCT05507164 · ClinicalTrials.gov registry record · Phase 2
Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
A Phase 2 study of Occlusion, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05507164: Recruiting Phase 2 study of Occlusion, sponsored by Rutgers, The State University of New Jersey.
NCT05507164 is a Phase 2 study of Occlusion that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05507164, a Phase 2 study of Occlusion, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience receiving the TMNB injection (secondary outcomes).
Primary Outcome
Left vs Right distribution of bite force upon clenching will be assessed as an average of 3 consequent measurements.
Conditions Studied
Interventions
- DRUG Temporomasseteric Nerve Block
Study Locations (1)
New Jersey
- Rutgers School of Dental Medicine - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-10-10 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT05507164 shows while recruiting
NCT05507164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Occlusion appearing as the primary indexed condition, and to 1 intervention - of which Temporomasseteric Nerve Block is the first listed.
NCT05507164 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05507164 about?
NCT05507164 is a clinical study titled "Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects". The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, w...
What is the current status of trial NCT05507164?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-10-10. Estimated completion is 2026-12.
What conditions does trial NCT05507164 study?
This clinical trial studies the following conditions: Occlusion.
What interventions are being tested in trial NCT05507164?
The interventions under investigation include: Temporomasseteric Nerve Block (DRUG).
Who is sponsoring clinical trial NCT05507164?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05507164 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05507164's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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