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NCT05501756 · ClinicalTrials.gov registry record · Phase 2

Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation

A Phase 2 study of Allogeneic Hematopoietic Cell Transplantation, sponsored by Children's Hospital Medical Center, Cincinnati.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT05501756 is a Phase 2 study of Allogeneic Hematopoietic Cell Transplantation that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 60 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05501756, a Phase 2 study of Allogeneic Hematopoietic Cell Transplantation, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

Alemtuzumab is an antibody that reduces the strength of the immune system that is given in preparation for allogeneic hematopoietic cell transplant (HCT). In this research study the investigators want to find out if they can adjust the dose of alemtuzumab used as part of allogeneic HCT to target the level of Day 0 (the planned day of graft infusion) to an optimal therapeutic window of 0.15-0.9 ug/mL.

Interventions

  • DRUG Alemtuzumab

Study Locations (1)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2023-01-11
Est. Completion 2028-08-31
Phase Phase 2

What the Registry Record Tells You About NCT05501756

The ClinicalTrials.gov registry entry for NCT05501756 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Allogeneic Hematopoietic Cell Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Alemtuzumab is the first listed.

NCT05501756 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05501756 about?

NCT05501756 is a clinical study titled "Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation". Alemtuzumab is an antibody that reduces the strength of the immune system that is given in preparation for allogeneic hematopoietic cell transplant (HCT). In this research study the investigators want to find out if they can adjust the dose of alemtuzumab used as part of allogeneic HCT to target the...

What is the current status of trial NCT05501756?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2023-01-11. Estimated completion is 2028-08-31.

What conditions does trial NCT05501756 study?

This clinical trial studies the following conditions: Allogeneic Hematopoietic Cell Transplantation.

What interventions are being tested in trial NCT05501756?

The interventions under investigation include: Alemtuzumab (DRUG).

Who is sponsoring clinical trial NCT05501756?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05501756 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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