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NCT05501600 · ClinicalTrials.gov registry record · Phase 1
Neural Correlates of Lidocaine Analgesia
A Phase 1 study, sponsored by Keith M Vogt.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
NCT05501600: Completed Phase 1 study, sponsored by Keith M Vogt.
NCT05501600 is a Phase 1 study that has completed, run by Keith M Vogt. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05501600, a Phase 1 study, has completed, sponsored by Keith M Vogt.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purpose of this study is to characterize the effects of intravenous lidocaine on pain processing and cognitive function. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will consist of 1 visit and involves no long-term follow up.
Primary Outcome
The Z-score is calculated by linear regression of the task timing against the MRI signal time-course (MRI data is in arbitrary units with no maximum or minimum) at each voxel (single data point in brain). Primary outcome is listed for the Right insula, but similar scores are calculated throughout the brain. Z-score of 0 indicates no task-related changes. Z-scores further from zero indicate stronger correlation between functional MRI signal change and the task timing, with positive values indicat
Interventions
- DRUG Lidocaine IV
- DEVICE Peripheral Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-11-22 |
| Est. Completion | 2023-11-17 |
| Phase | Phase 1 |
What the finished NCT05501600 record still lists
NCT05501600 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 2 interventions - of which Lidocaine IV is the first listed.
NCT05501600 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05501600 about?
NCT05501600 is a clinical study titled "Neural Correlates of Lidocaine Analgesia". The purpose of this study is to characterize the effects of intravenous lidocaine on pain processing and cognitive function. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will consist of 1 visit and involves no long-term follow up.
What is the current status of trial NCT05501600?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2022-11-22. Estimated completion is 2023-11-17.
What interventions are being tested in trial NCT05501600?
The interventions under investigation include: Lidocaine IV (DRUG), Peripheral Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05501600?
This trial is sponsored by Keith M Vogt, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05501600's enrollment target sits among peer trials
30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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