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NCT05501262 · ClinicalTrials.gov registry record · NA
Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma
A NA study of Morton Neuroma, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT05501262: Recruiting NA study of Morton Neuroma, sponsored by Oregon Health and Science University.
NCT05501262 is a NA study of Morton Neuroma that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05501262, a NA study of Morton Neuroma, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
Morton's neuroma is a benign thickening involving the plantar interdigital nerve, most common in middle aged women. Morton's neuroma is one of the most frequent diagnoses seen in the investigators podiatry clinic and is difficult to treat. These lesions cause a burning or shooting pain that can radiate to the toes, or an aching pain in the ball of the foot. The pain is exacerbated with activity and certain footwear greatly limits activity in the involved patient population. Morton's neuroma is first treated conservatively with orthotics. Patients may require further interventions such as steroid injections. The literature reports only a 30% long term resolution of pain with the steroid. Surgical resection has a reported 51-85% success rate with 14-21% rate of complication; recurrent pain, numbness/loss of sensation, and subsequent stump neuromas. Cryoablation is well known to be efficacious for neuropathic pain and has recently been shown in two small studies to be safe and efficacious for treatment of Morton's neuroma. The investigators study will compare outcomes of cryoablation to corticosteroid injection in short- and long-term for treatment of Morton's neuroma that have failed conservative therapy.
Primary Outcome
Will be evaluated using the SF-36 Quality of Life Survey
Conditions Studied
Interventions
- DEVICE Cryoablation
- PROCEDURE Nerve block
Study Locations (1)
Oregon
- Oregon Health Sciences University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2022-07-25 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What NCT05501262 shows while recruiting
NCT05501262 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Morton Neuroma appearing as the primary indexed condition, and to 2 interventions - of which Cryoablation is the first listed.
NCT05501262 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT05501262 about?
NCT05501262 is a clinical study titled "Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma". Morton's neuroma is a benign thickening involving the plantar interdigital nerve, most common in middle aged women. Morton's neuroma is one of the most frequent diagnoses seen in the investigators podiatry clinic and is difficult to treat. These lesions cause a burning or shooting pain that can radi...
What is the current status of trial NCT05501262?
This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2022-07-25. Estimated completion is 2027-12-31.
What conditions does trial NCT05501262 study?
This clinical trial studies the following conditions: Morton Neuroma.
What interventions are being tested in trial NCT05501262?
The interventions under investigation include: Cryoablation (DEVICE), Nerve block (PROCEDURE).
Who is sponsoring clinical trial NCT05501262?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05501262 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05501262's enrollment target sits among peer trials
32 1579th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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