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NCT05495945 · ClinicalTrials.gov registry record · Phase 2
Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
A Phase 2 study, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 2
- Development phase
- 13
- Enrollment target
NCT05495945: Completed Phase 2 study, sponsored by University of Michigan.
NCT05495945 is a Phase 2 study that has completed, run by University of Michigan. The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05495945, a Phase 2 study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 13 participants
- Enrollment target
Study Summary
The purpose of this study is to see if mental functions take place during different levels of anesthesia. The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to consciousness.
Primary Outcome
BOLD signal was measured by Magnetic Resonance Imaging (MRI) scanning of the brain in response to a visual stimuli. This method reflected changes in oxygenation of blood in the brain during a scene-processing task.
Interventions
- DEVICE Low-intensity focused ultrasound pulsation (LIFUP)
- COMBINATION_PRODUCT Functional Magnetic Resonance Imaging (fMRI) using Propofol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2022-08-26 |
| Est. Completion | 2023-10-07 |
| Phase | Phase 2 |
What the finished NCT05495945 record still lists
NCT05495945 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Low-intensity focused ultrasound pulsation (LIFUP) is the first listed.
NCT05495945 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05495945 about?
NCT05495945 is a clinical study titled "Ultrasonic Deep Brain Stimulation During Anesthetic Sedation". The purpose of this study is to see if mental functions take place during different levels of anesthesia. The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to c...
What is the current status of trial NCT05495945?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2022-08-26. Estimated completion is 2023-10-07.
What interventions are being tested in trial NCT05495945?
The interventions under investigation include: Low-intensity focused ultrasound pulsation (LIFUP) (DEVICE), Functional Magnetic Resonance Imaging (fMRI) using Propofol (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05495945?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05495945's enrollment target sits among peer trials
13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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