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NCT05488873 · ClinicalTrials.gov registry record · Phase 2
A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy
A Phase 2 study of Chemotherapy-induced Peripheral Neuropathy, sponsored by WinSanTor.
- Active
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05488873: Active Phase 2 study of Chemotherapy-induced Peripheral Neuropathy, sponsored by WinSanTor.
NCT05488873 is a Phase 2 study of Chemotherapy-induced Peripheral Neuropathy that is active but no longer recruiting, run by WinSanTor. The registered enrollment target is 60 participants, below the 136-participant average among 29 other Chemotherapy-induced Peripheral Neuropathy trials with a reported enrollment target (56% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05488873, a Phase 2 study of Chemotherapy-induced Peripheral Neuropathy, is active but no longer recruiting, sponsored by WinSanTor.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized, double-blind, placebo-controlled adaptive study of the safety, tolerability, and exploratory efficacy of once-daily topical WST-057 administered for up to 19 weeks (or up to 24 weeks for subjects who experience a chemotherapy dose delay) to subjects who are also receiving 6 cycles (3 weeks apart) of Carboplatin AUC 5-6 and Paclitaxel 175 mg/m2 (with dose adjustment per institutional guidelines permitted).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG WST-057 Active
Study Locations (1)
North Carolina
- Levine Cancer Institute - Charlotte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-11-22 |
| Est. Completion | 2026-05-30 |
| Phase | Phase 2 |
What the registry record for NCT05488873 still lists
NCT05488873 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 136-participant average among 29 other Chemotherapy-induced Peripheral Neuropathy trials with a reported enrollment target (56% lower).
The record links to 1 condition, with Chemotherapy-induced Peripheral Neuropathy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05488873 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT05488873 about?
NCT05488873 is a clinical study titled "A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy". This is a randomized, double-blind, placebo-controlled adaptive study of the safety, tolerability, and exploratory efficacy of once-daily topical WST-057 administered for up to 19 weeks (or up to 24 weeks for subjects who experience a chemotherapy dose delay) to subjects who are also receiving 6 cyc...
What is the current status of trial NCT05488873?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2022-11-22. Estimated completion is 2026-05-30.
What conditions does trial NCT05488873 study?
This clinical trial studies the following conditions: Chemotherapy-induced Peripheral Neuropathy.
What interventions are being tested in trial NCT05488873?
The interventions under investigation include: Placebo (DRUG), WST-057 Active (DRUG).
Who is sponsoring clinical trial NCT05488873?
This trial is sponsored by WinSanTor, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05488873 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chemotherapy-induced Peripheral Neuropathy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05488873's enrollment target sits among peer trials
60 13th of 29 higher than 17 of 29 other Chemotherapy-induced Peripheral Neuropathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chemotherapy-induced Peripheral Neuropathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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