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NCT05488678 · ClinicalTrials.gov registry record · Phase 1

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

A Phase 1 study, sponsored by Basilea Pharmaceutica.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target

NCT05488678 is a Phase 1 study that has completed, run by Basilea Pharmaceutica. The registered enrollment target is 32 participants.

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The verdict

NCT05488678, a Phase 1 study, has completed, sponsored by Basilea Pharmaceutica.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

This is an open-label, multicenter, parallel-group study in participants with normal renal function, mild, moderate, or severe renal impairment, or end stage renal disease (ESRD) undergoing standard intermittent dialysis. The pharmacokinetics (PK) of the inactive prodrug VNRX-7145, its active parent drug VNRX-5236, and ceftibuten will be evaluated after a single oral dose of ceftibuten/VNRX-7145.

Interventions

  • DRUG Ceftibuten
  • DRUG VNRX-7145

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2022-10-12
Est. Completion 2023-11-23
Phase Phase 1

Sponsor

Basilea Pharmaceutica

21 total trials

What the Registry Record Tells You About NCT05488678

The ClinicalTrials.gov registry entry for NCT05488678 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Basilea Pharmaceutica, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Ceftibuten is the first listed.

NCT05488678 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05488678 about?

NCT05488678 is a clinical study titled "Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function". This is an open-label, multicenter, parallel-group study in participants with normal renal function, mild, moderate, or severe renal impairment, or end stage renal disease (ESRD) undergoing standard intermittent dialysis. The pharmacokinetics (PK) of the inactive prodrug VNRX-7145, its active parent...

What is the current status of trial NCT05488678?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2022-10-12. Estimated completion is 2023-11-23.

What interventions are being tested in trial NCT05488678?

The interventions under investigation include: Ceftibuten (DRUG), VNRX-7145 (DRUG).

Who is sponsoring clinical trial NCT05488678?

This trial is sponsored by Basilea Pharmaceutica, which has 21 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.