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NCT05487183 · ClinicalTrials.gov registry record · NA
Test Retest Reliability of OA and OH
A NA study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- NA
- Development phase
- 74
- Enrollment target
NCT05487183: Completed NA study, sponsored by University of Pittsburgh.
NCT05487183 is a NA study that has completed, run by University of Pittsburgh. The registered enrollment target is 74 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05487183, a NA study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- NA
- Development phase
- 74 participants
- Enrollment target
Study Summary
The goal of this study is to measure the test retest reliability of offset analgesia (OA) and onset hyperalgesia (OH) across multiple study visits. OA and OH are quantitative sensory tests (QST) thought to measure how the brain modulates pain. This study will use a heat thermode to induce OA and OH in healthy, pain-free volunteers across 3 study visits. Additional QST measures and survey data relevant to pain modulation will be collected. This study lays the foundation required to use OA and OH as tools to measure pain modulation in clinical trials. Following their validation, we anticipate that OA and OH will serve as predictive and therapeutic biomarkers, which will aid both in the development of novel analgesics and in treatment selection leading to the personalization of pain management.
Primary Outcome
Pain intensity difference during heat stimuli measured on a 0-100 sliding scale (0 is no pain, 100 is the most intense pain imaginable) at baseline
Interventions
- BEHAVIORAL Medoc cutaneous probe
- BEHAVIORAL Quantitative sensory testing
- BEHAVIORAL Computer tasks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2022-08-05 |
| Est. Completion | 2024-04-10 |
| Phase | NA |
What the finished NCT05487183 record still lists
NCT05487183 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 3 interventions - of which Medoc cutaneous probe is the first listed.
NCT05487183 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05487183 about?
NCT05487183 is a clinical study titled "Test Retest Reliability of OA and OH". The goal of this study is to measure the test retest reliability of offset analgesia (OA) and onset hyperalgesia (OH) across multiple study visits. OA and OH are quantitative sensory tests (QST) thought to measure how the brain modulates pain. This study will use a heat thermode to induce OA and OH ...
What is the current status of trial NCT05487183?
This trial is currently completed. It is a NA study. The enrollment target is 74 participants. The study started on 2022-08-05. Estimated completion is 2024-04-10.
What interventions are being tested in trial NCT05487183?
The interventions under investigation include: Medoc cutaneous probe (BEHAVIORAL), Quantitative sensory testing (BEHAVIORAL), Computer tasks (BEHAVIORAL).
Who is sponsoring clinical trial NCT05487183?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05487183's enrollment target sits among peer trials
74 1082nd of 2000 higher than 912 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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