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NCT05474027 · ClinicalTrials.gov registry record · Phase 4
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
A Phase 4 study, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- Phase 4
- Development phase
- 115
- Enrollment target
NCT05474027 is a Phase 4 study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 115 participants.
The verdict
NCT05474027, a Phase 4 study, has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 115 participants
- Enrollment target
Study Summary
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered. DHA has been proven to be effective although it comes with multiple risks related to organ hypoperfusion including kidney injury, stroke, and cardiac ischemia. Therefore, it may be potentially safer for patients to avoid deliberate hypotensive anesthesia if TXA alone adequately controls blood loss and provides adequate surgical site visualization.
Interventions
- OTHER Avoidance of Deliberate Hypotensive Anesthesia
- DRUG TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 115 participants |
| Start Date | 2022-11-11 |
| Est. Completion | 2025-12-01 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05474027
The ClinicalTrials.gov registry entry for NCT05474027 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 115 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Avoidance of Deliberate Hypotensive Anesthesia is the first listed.
NCT05474027 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05474027 about?
NCT05474027 is a clinical study titled "Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery". This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered. DHA has been proven to be effective although it comes with multiple risks related to organ hypoperfusion including kidney injury, stroke, a...
What is the current status of trial NCT05474027?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 115 participants. The study started on 2022-11-11. Estimated completion is 2025-12-01.
What interventions are being tested in trial NCT05474027?
The interventions under investigation include: Avoidance of Deliberate Hypotensive Anesthesia (OTHER), TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION (DRUG).
Who is sponsoring clinical trial NCT05474027?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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