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NCT05468749 · ClinicalTrials.gov registry record · Phase 1
Study to Assess the Effect of Renal Impairment on the Pharmacokinetics of CTP-543
A Phase 1 study, sponsored by Concert Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT05468749: Completed Phase 1 study, sponsored by Concert Pharmaceuticals.
NCT05468749 is a Phase 1 study that has completed, run by Concert Pharmaceuticals. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05468749, a Phase 1 study, has completed, sponsored by Concert Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This is an open-label, single-dose, sequentially designed, single-period study to determine the effect of moderate renal impairment on the pharmacokinetics (PK) of CTP-543 and its major metabolites following administration of a single 12 mg oral dose of CTP-543.
Primary Outcome
Maximum concentration, obtained directly from the observed concentration versus time data.
Interventions
- DRUG CTP-543
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2022-06-06 |
| Est. Completion | 2022-10-27 |
| Phase | Phase 1 |
What the finished NCT05468749 record still lists
NCT05468749 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 1 intervention - of which CTP-543 is the first listed.
NCT05468749 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05468749 about?
NCT05468749 is a clinical study titled "Study to Assess the Effect of Renal Impairment on the Pharmacokinetics of CTP-543". This is an open-label, single-dose, sequentially designed, single-period study to determine the effect of moderate renal impairment on the pharmacokinetics (PK) of CTP-543 and its major metabolites following administration of a single 12 mg oral dose of CTP-543.
What is the current status of trial NCT05468749?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2022-06-06. Estimated completion is 2022-10-27.
What interventions are being tested in trial NCT05468749?
The interventions under investigation include: CTP-543 (DRUG).
Who is sponsoring clinical trial NCT05468749?
This trial is sponsored by Concert Pharmaceuticals, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05468749's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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