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NCT05462782 · ClinicalTrials.gov registry record · NA

TMS for Investigating Memory Facilitation

A NA study, sponsored by Shirley Ryan AbilityLab.

Terminated
Registry status
NA
Development phase
1
Enrollment target

NCT05462782: Clinical Trial NA study, sponsored by Shirley Ryan AbilityLab.

NCT05462782 is a NA study that was terminated before completion, run by Shirley Ryan AbilityLab. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05462782, a NA study, was terminated before completion, sponsored by Shirley Ryan AbilityLab.

TERMINATED
Registry status
NA
Development phase
1 participants
Enrollment target

Study Summary

The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals. For this purpose, we will apply TMS synchronized with a working memory (WM) task and assess its effects on cortical connectivity and memorization capacity by Magnetic Resonance Imaging (MRI) and WM task learning. This study will be carried out in an older population of healthy participants. We will use the study results to refine the task related PAS protocol towards enhancing memory performance and brain connectivity.

Primary Outcome

The WM task utilized is a customized version of the masking task model, presented by Sana Inoue and Tetsuro Matsuzawa, in 2007. This task is organized in three phases: 1) Waiting phase: a visual cue is presented to indicate the initiation of the trial; 2) Coding and retention phase: numbers are presented in a random arrangement within a 5x5 square matrix; and 3) Recall phase: the numbers disappear, leaving a white background as a clue, and the subject completes the task by pressing the squares i

Interventions

  • DEVICE Transcranial Magnetic Stimulation (TMS) Cone Coil
  • DEVICE Transcranial Magnetic Stimulation (TMS) Sham Coil

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2022-08-05
Est. Completion 2023-04-03
Phase NA
Shirley Ryan AbilityLab

138 total trials

Why NCT05462782 stopped before completion

NCT05462782 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 2 interventions - of which Transcranial Magnetic Stimulation (TMS) Cone Coil is the first listed.

NCT05462782 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05462782 about?

NCT05462782 is a clinical study titled "TMS for Investigating Memory Facilitation". The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals. For this purpose, we will apply TMS synchronized with a working memory (WM) task and assess it...

What is the current status of trial NCT05462782?

This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2022-08-05. Estimated completion is 2023-04-03.

What interventions are being tested in trial NCT05462782?

The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) Cone Coil (DEVICE), Transcranial Magnetic Stimulation (TMS) Sham Coil (DEVICE).

Who is sponsoring clinical trial NCT05462782?

This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05462782's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05462782, the US trial registry maintained by the National Library of Medicine. NCT05462782 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.