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NCT05459558 · ClinicalTrials.gov registry record · NA
Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
A NA study, sponsored by HALEON.
- Completed
- Registry status
- NA
- Development phase
- 280
- Enrollment target
NCT05459558: Completed NA study, sponsored by HALEON.
NCT05459558 is a NA study that has completed, run by HALEON. The registered enrollment target is 280 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05459558, a NA study, has completed, sponsored by HALEON.
- COMPLETED
- Registry status
- NA
- Development phase
- 280 participants
- Enrollment target
Study Summary
The aim of this study is to investigate the stain removal efficacy of 2 experimental anti-dentin hypersensitivity (DH) dentifrices with four and eight weeks twice daily use. A daily use, regular fluoride dentifrice will be included as a reference dentifrice.
Primary Outcome
Extrinsic dental stain area and its intensity were assessed on the facial surfaces of the 6 maxillary and 6 mandibular anterior teeth and the lingual surfaces of the 6 mandibular anterior teeth. MLSI score= Area score multiplied by Intensity score. Area and intensity of extrinsic dental stain were scored separately for each tooth on the scale 0 to 3, where 0= area with no stain, 1= Stain covering up to one third of area and light intensity stain, 2= Stain covering up to two thirds of area and mo
Interventions
- DRUG Reference Dentifrice
- DRUG Experimental Dentifrice 1
- DRUG Experimental Dentifrice 2
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2022-09-15 |
| Est. Completion | 2022-12-04 |
| Phase | NA |
What the finished NCT05459558 record still lists
NCT05459558 is an interventional study that assigns participants to a tested intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 3 interventions - of which Reference Dentifrice is the first listed.
NCT05459558 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05459558 about?
NCT05459558 is a clinical study titled "Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks". The aim of this study is to investigate the stain removal efficacy of 2 experimental anti-dentin hypersensitivity (DH) dentifrices with four and eight weeks twice daily use. A daily use, regular fluoride dentifrice will be included as a reference dentifrice.
What is the current status of trial NCT05459558?
This trial is currently completed. It is a NA study. The enrollment target is 280 participants. The study started on 2022-09-15. Estimated completion is 2022-12-04.
What interventions are being tested in trial NCT05459558?
The interventions under investigation include: Reference Dentifrice (DRUG), Experimental Dentifrice 1 (DRUG), Experimental Dentifrice 2 (DRUG).
Who is sponsoring clinical trial NCT05459558?
This trial is sponsored by HALEON, which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05459558's enrollment target sits among peer trials
280 380th of 2000 higher than 1,620 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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