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NCT05457218 · ClinicalTrials.gov registry record · NA
Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation
A NA study of Effect of Food Supplement, sponsored by University of California, Davis.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05457218 is a NA study of Effect of Food Supplement that has completed, run by University of California, Davis. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05457218, a NA study of Effect of Food Supplement, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine the ability of insect-derived protein supplements (IPC80 and Whole Buffalo Powder Ynsect®) to activate the mTORC1 pathway and protein synthesis in muscle cells. To achieve this aim, participants will consume a supplemental dose (0.25 g/kg body weight) of IPC80,Whole Buffalo Powder or whey protein. Blood samples will be drawn before and 15, 30, 60 and 90 minutes after the supplementation. Protein synthesis will be assessed using stably transfected C2C12 muscle cells with a plasmid (pcDNA3 luciferase) and to determine the ability of a protein source to activate mTORC1, stably transfected C2C12 muscle cells with a plasmid (pcDNA3-TOP luciferase) where the luciferase mRNA contains a 5'TOP. 5'TOP which is specifically regulated by mTORC1 activity will be used.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Whey protein
- DIETARY_SUPPLEMENT IPC80
- DIETARY_SUPPLEMENT Whole Buffalo Powder
Study Locations (1)
California
- Hickey Laboratory - Davis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-10-01 |
| Est. Completion | 2024-09-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05457218
The ClinicalTrials.gov registry entry for NCT05457218 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Effect of Food Supplement appearing as the primary indexed condition, and to 3 interventions - of which Whey protein is the first listed.
NCT05457218 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05457218 about?
NCT05457218 is a clinical study titled "Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation". The purpose of this study is to determine the ability of insect-derived protein supplements (IPC80 and Whole Buffalo Powder Ynsect®) to activate the mTORC1 pathway and protein synthesis in muscle cells. To achieve this aim, participants will consume a supplemental dose (0.25 g/kg body weight) of IP...
What is the current status of trial NCT05457218?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2022-10-01. Estimated completion is 2024-09-30.
What conditions does trial NCT05457218 study?
This clinical trial studies the following conditions: Effect of Food Supplement.
What interventions are being tested in trial NCT05457218?
The interventions under investigation include: Whey protein (DIETARY_SUPPLEMENT), IPC80 (DIETARY_SUPPLEMENT), Whole Buffalo Powder (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05457218?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05457218 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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