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NCT05445440 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of Sulfasalazine
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
NCT05445440: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT05445440 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05445440, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effects of BMS-986371 on the drug levels of methotrexate, sulfasalazine and their main metabolites in healthy male adult participants.
Primary Outcome
Part 1
Interventions
- DRUG Leucovorin
- DRUG Methotrexate
- DRUG Sulfasalazine
- DRUG BMS-986371
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-09-06 |
| Est. Completion | 2022-11-23 |
| Phase | Phase 1 |
What the finished NCT05445440 record still lists
NCT05445440 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 4 interventions - of which Leucovorin is the first listed.
NCT05445440 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05445440 about?
NCT05445440 is a clinical study titled "A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of Sulfasalazine". The purpose of this study is to evaluate the effects of BMS-986371 on the drug levels of methotrexate, sulfasalazine and their main metabolites in healthy male adult participants.
What is the current status of trial NCT05445440?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2022-09-06. Estimated completion is 2022-11-23.
What interventions are being tested in trial NCT05445440?
The interventions under investigation include: Leucovorin (DRUG), Methotrexate (DRUG), Sulfasalazine (DRUG), BMS-986371 (DRUG).
Who is sponsoring clinical trial NCT05445440?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05445440's enrollment target sits among peer trials
30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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