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NCT05428215 · ClinicalTrials.gov registry record · Phase 4
Comparison of PKs of 17-Beta-Estradiol Via Sublingual Placement Versus Swallowing in Male-to-Female Transgender Patients
A Phase 4 study, sponsored by MaineHealth.
- Terminated
- Registry status
- Phase 4
- Development phase
- 2
- Enrollment target
NCT05428215: Clinical Trial Phase 4 study, sponsored by MaineHealth.
NCT05428215 is a Phase 4 study that was terminated before completion, run by MaineHealth. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05428215, a Phase 4 study, was terminated before completion, sponsored by MaineHealth.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 2 participants
- Enrollment target
Study Summary
This crossover study will investigate the pharmacokinetics of oral versus sublingual administration of 17-beta-estradiol in the trans-female population.
Primary Outcome
Mean area under the curve of estradiol
Interventions
- DRUG 17beta Estradiol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2022-12-29 |
| Est. Completion | 2023-07-20 |
| Phase | Phase 4 |
Why NCT05428215 stopped before completion
NCT05428215 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which 17beta Estradiol is the first listed.
NCT05428215 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05428215 about?
NCT05428215 is a clinical study titled "Comparison of PKs of 17-Beta-Estradiol Via Sublingual Placement Versus Swallowing in Male-to-Female Transgender Patients". This crossover study will investigate the pharmacokinetics of oral versus sublingual administration of 17-beta-estradiol in the trans-female population.
What is the current status of trial NCT05428215?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2022-12-29. Estimated completion is 2023-07-20.
What interventions are being tested in trial NCT05428215?
The interventions under investigation include: 17beta Estradiol (DRUG).
Who is sponsoring clinical trial NCT05428215?
This trial is sponsored by MaineHealth, which has 26 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05428215's enrollment target sits among peer trials
2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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