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NCT05379400 · ClinicalTrials.gov registry record · NA
Cleaner Air for Better Cardiac Biomarkers
A NA study, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
NCT05379400: Completed NA study, sponsored by NYU Langone Health.
NCT05379400 is a NA study that has completed, run by NYU Langone Health. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05379400, a NA study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
Study Summary
This pilot project is a randomized, double-blind, sham-controlled trial investigating whether in-home air pollution reductions using portable air cleaners (PACs) can decrease circulating concentrations of biomarkers of inflammation. Using both a targeted approach to study the established biomarker TNFa and an exploratory approach with a commercially available proteomic panel, the researchers will measure concentrations of biomarkers before and after four weeks of home PAC use in a cohort of 74 adults with hypertension recruited from NYU outpatient clinical settings. Participants will also track home blood pressure measurements for additional exploratory analysis of potential mediation of PAC-associated decreases in blood pressure by biomarker concentration changes.
Primary Outcome
Circulating concentrations of TNFα will be measured using the Olink Explore 384 Cardiometabolic panel for this a priori specified analysis.
Interventions
- OTHER Portable air cleaner (PAC)
- OTHER Sham Portable air cleaner (PAC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-08-11 |
| Est. Completion | 2023-08-24 |
| Phase | NA |
What the finished NCT05379400 record still lists
NCT05379400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Portable air cleaner (PAC) is the first listed.
NCT05379400 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05379400 about?
NCT05379400 is a clinical study titled "Cleaner Air for Better Cardiac Biomarkers". This pilot project is a randomized, double-blind, sham-controlled trial investigating whether in-home air pollution reductions using portable air cleaners (PACs) can decrease circulating concentrations of biomarkers of inflammation. Using both a targeted approach to study the established biomarker T...
What is the current status of trial NCT05379400?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2022-08-11. Estimated completion is 2023-08-24.
What interventions are being tested in trial NCT05379400?
The interventions under investigation include: Portable air cleaner (PAC) (OTHER), Sham Portable air cleaner (PAC) (OTHER).
Who is sponsoring clinical trial NCT05379400?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05379400's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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