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NCT05363020 · ClinicalTrials.gov registry record · Phase 4
S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands
A Phase 4 study, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
NCT05363020: Completed Phase 4 study, sponsored by Dartmouth-Hitchcock Medical Center.
NCT05363020 is a Phase 4 study that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05363020, a Phase 4 study, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
Study Summary
The primary objective of this study is to demonstrate the feasibility of evaluating SAMe tolerability, analgesic benefits, and daily functional improvement in patients with osteoarthritis of the hands compared to placebo. The secondary objective of this study is to generate preliminary data on discomfort, function, quality of life in patients with osteoarthritis of the hands when taking SAMe compared to placebo.
Primary Outcome
Scores range from 0-10, 0 being no discomfort and 10 being maximum discomfort
Interventions
- DRUG Placebo
- DRUG S-Adenosyl-L-Methionine (Sam-E)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2022-08-17 |
| Est. Completion | 2025-04-11 |
| Phase | Phase 4 |
What the finished NCT05363020 record still lists
NCT05363020 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05363020 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05363020 about?
NCT05363020 is a clinical study titled "S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands". The primary objective of this study is to demonstrate the feasibility of evaluating SAMe tolerability, analgesic benefits, and daily functional improvement in patients with osteoarthritis of the hands compared to placebo. The secondary objective of this study is to generate preliminary data on disco...
What is the current status of trial NCT05363020?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2022-08-17. Estimated completion is 2025-04-11.
What interventions are being tested in trial NCT05363020?
The interventions under investigation include: Placebo (DRUG), S-Adenosyl-L-Methionine (Sam-E) (DRUG).
Who is sponsoring clinical trial NCT05363020?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05363020's enrollment target sits among peer trials
40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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