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NCT05359965 · ClinicalTrials.gov registry record · NA
Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF
A NA study, sponsored by University of Arizona.
- Terminated
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT05359965: Clinical Trial NA study, sponsored by University of Arizona.
NCT05359965 is a NA study that was terminated before completion, run by University of Arizona. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05359965, a NA study, was terminated before completion, sponsored by University of Arizona.
- TERMINATED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
This study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
Primary Outcome
The primary outcome will be a composite value that is a weighted average of z-scores of the biomarkers MMP1, MMP7, IL-8, KL-6, and CXCL13, weighted by the univariate effect sizes of each biomarker. MMP1, MMP7, IL-8, KL-6, and CXCL13 will be measured using enzyme linked immunosorbent assays (ELISA) for these analytes. (Z-score is a unitless number, as is the weighted average.)
Interventions
- DEVICE Positive Airway Pressure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2019-10-01 |
| Est. Completion | 2025-02-11 |
| Phase | NA |
Why NCT05359965 stopped before completion
NCT05359965 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Positive Airway Pressure is the first listed.
NCT05359965 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05359965 about?
NCT05359965 is a clinical study titled "Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF". This study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
What is the current status of trial NCT05359965?
This trial is currently terminated. It is a NA study. The enrollment target is 7 participants. The study started on 2019-10-01. Estimated completion is 2025-02-11.
What interventions are being tested in trial NCT05359965?
The interventions under investigation include: Positive Airway Pressure (DEVICE).
Who is sponsoring clinical trial NCT05359965?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05359965's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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