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NCT05357170 · ClinicalTrials.gov registry record

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

A clinical trial of Sepsis, Trauma Injury, sponsored by University of Florida.

Recruiting
Registry status
468
Enrollment target
1
Study location

NCT05357170 is a study of Sepsis, Trauma Injury that is actively recruiting participants, run by University of Florida. The registered enrollment target is 468 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05357170, a study of Sepsis, Trauma Injury, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
468 participants
Enrollment target
1
Study location

Study Summary

Oral and gastrointestinal microbiome dysfunction has been demonstrated to be a culprit of various systemic dysfunctions in peripheries such as cardiovascular, nervous, endocrine and musculoskeletal systems. The topic of microbiome dysfunction after surgical intensive care admission is understudied but may be responsible for persistent systemic inflammation clinically observed in surgical intensive care patients. Therefore, the objective of this project is to investigate the oral and gut microbiome after the acute phase of sepsis, severe trauma injury, cardiopulmonary bypass, and major vascular surgery to compare with 108 age-matched healthy population controls

Conditions Studied

Interventions

  • OTHER Human feces collection

Study Locations (1)

Florida

  • UF Health at Shands Hospital - Gainesville

Trial Details

FieldValue
Enrollment Target 468 participants
Start Date 2022-06-21
Est. Completion 2028-05-31

Sponsor

University of Florida

1,106 total trials

What the Registry Record Tells You About NCT05357170

The ClinicalTrials.gov registry entry for NCT05357170 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 468 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Sepsis, Trauma Injury appearing as the primary indexed condition, and to 1 intervention - of which Human feces collection is the first listed.

NCT05357170 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05357170 about?

NCT05357170 is a clinical study titled "Microbiome Dysfunction in Surgical Intensive Care Unit Survivors". Oral and gastrointestinal microbiome dysfunction has been demonstrated to be a culprit of various systemic dysfunctions in peripheries such as cardiovascular, nervous, endocrine and musculoskeletal systems. The topic of microbiome dysfunction after surgical intensive care admission is understudied b...

What is the current status of trial NCT05357170?

This trial is currently recruiting. The enrollment target is 468 participants. The study started on 2022-06-21. Estimated completion is 2028-05-31.

What conditions does trial NCT05357170 study?

This clinical trial studies the following conditions: Sepsis, Trauma Injury.

What interventions are being tested in trial NCT05357170?

The interventions under investigation include: Human feces collection (OTHER).

Who is sponsoring clinical trial NCT05357170?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05357170 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.