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NCT05356286 · ClinicalTrials.gov registry record · NA
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
A NA study of Spondylosis and Cervical Stenosis, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT05356286: Recruiting NA study of Spondylosis and Cervical Stenosis, sponsored by University of California, Los Angeles.
NCT05356286 is a NA study of Spondylosis and Cervical Stenosis that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 150 participants, above the 54-participant average among 8 other Spondylosis trials with a reported enrollment target (178% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05356286, a NA study of Spondylosis and Cervical Stenosis, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.
Primary Outcome
Increase or decrease in respiratory frequency of 20% during or after stimulation
Conditions Studied
Interventions
- DEVICE epidural electrical stimulation
Study Locations (1)
California
- University of California, Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2011-01-21 |
| Est. Completion | 2027-01-22 |
| Phase | NA |
What NCT05356286 shows while recruiting
NCT05356286 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 54-participant average among 8 other Spondylosis trials with a reported enrollment target (178% higher).
The record links to 3 conditions, with Spondylosis appearing as the primary indexed condition, and to 1 intervention - of which epidural electrical stimulation is the first listed.
NCT05356286 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05356286 about?
NCT05356286 is a clinical study titled "Recording of Intraoperative Spinal Cord Stimulation and Monitoring". Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induc...
What is the current status of trial NCT05356286?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2011-01-21. Estimated completion is 2027-01-22.
What conditions does trial NCT05356286 study?
This clinical trial studies the following conditions: Spondylosis, Cervical Stenosis, Disk, Herniated.
What interventions are being tested in trial NCT05356286?
The interventions under investigation include: epidural electrical stimulation (DEVICE).
Who is sponsoring clinical trial NCT05356286?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05356286 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spondylosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05356286's enrollment target sits among peer trials
150 1st of 8 higher than 8 of 8 other Spondylosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spondylosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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