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NCT05355974 · ClinicalTrials.gov registry record · Phase 3

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

A Phase 3 study, sponsored by Wright State University.

Completed
Registry status
Phase 3
Development phase
42
Enrollment target

NCT05355974: Completed Phase 3 study, sponsored by Wright State University.

NCT05355974 is a Phase 3 study that has completed, run by Wright State University. The registered enrollment target is 42 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05355974, a Phase 3 study, has completed, sponsored by Wright State University.

COMPLETED
Registry status
Phase 3
Development phase
42 participants
Enrollment target

Study Summary

The purpose of this study is to investigate whether protocolized vasopressor use for patients with normal blood pressure undergoing rapid sequence intubation improves hemodynamic parameters and mitigates adverse events. The hypothesis is that use of vasopressors during Rapid Sequence Intubation will prevent substantial decreases in blood pressure when compared to normal intravenous fluids.

Primary Outcome

Change in systolic blood pressure during rapid sequence intubation in mmHg.

Interventions

  • DRUG Norepinephrine
  • DRUG normal saline
  • DRUG Lactated Ringers, Intravenous
  • DRUG Plasma-lyte

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2022-08-09
Est. Completion 2024-07-10
Phase Phase 3
Wright State University

32 total trials

What the finished NCT05355974 record still lists

NCT05355974 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 4 interventions - of which Norepinephrine is the first listed.

NCT05355974 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05355974 about?

NCT05355974 is a clinical study titled "Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure". The purpose of this study is to investigate whether protocolized vasopressor use for patients with normal blood pressure undergoing rapid sequence intubation improves hemodynamic parameters and mitigates adverse events. The hypothesis is that use of vasopressors during Rapid Sequence Intubation wil...

What is the current status of trial NCT05355974?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 42 participants. The study started on 2022-08-09. Estimated completion is 2024-07-10.

What interventions are being tested in trial NCT05355974?

The interventions under investigation include: Norepinephrine (DRUG), normal saline (DRUG), Lactated Ringers, Intravenous (DRUG), Plasma-lyte (DRUG).

Who is sponsoring clinical trial NCT05355974?

This trial is sponsored by Wright State University, which has 32 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05355974's enrollment target sits among peer trials

42 1877th of 2000 higher than 124 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05355974, the US trial registry maintained by the National Library of Medicine. NCT05355974 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.