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NCT05355883 · ClinicalTrials.gov registry record · NA
Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability
A NA study, sponsored by East Carolina University.
- Completed
- Registry status
- NA
- Development phase
- 51
- Enrollment target
NCT05355883: Completed NA study, sponsored by East Carolina University.
NCT05355883 is a NA study that has completed, run by East Carolina University. The registered enrollment target is 51 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05355883, a NA study, has completed, sponsored by East Carolina University.
- COMPLETED
- Registry status
- NA
- Development phase
- 51 participants
- Enrollment target
Study Summary
Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's independence. The existing therapeutic interventions have higher training doses and modest effect sizes. Thus, there is a critical need to find an effective priming agent to enhance bimanual skill learning in children with UCP. This study aims to determine the effects of a novel priming agent, remote ischemic conditioning (RIC), when paired with intensive bimanual skill training to enhance bimanual skill learning and to augment skill dependent plasticity in children with UCP.
Primary Outcome
Assisting Hand Assessment assesses bimanual coordination and affected hand function. A 5-point change from pre- to post-intervention is considered a clinically meaningful improvement.
Interventions
- BEHAVIORAL Sham conditioning
- BEHAVIORAL Balance training
- BEHAVIORAL Remote Ischemic Conditioning (RIC)
- BEHAVIORAL Hand Arm Bimanual Intensive Therapy (HABIT)
- BEHAVIORAL Bimanual Cup Stacking Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2021-12-18 |
| Est. Completion | 2025-05-30 |
| Phase | NA |
What the finished NCT05355883 record still lists
NCT05355883 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 5 interventions - of which Sham conditioning is the first listed.
NCT05355883 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05355883 about?
NCT05355883 is a clinical study titled "Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability". Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's independence. The existing therapeutic interventions have higher training doses and modest effect sizes. Thus, there ...
What is the current status of trial NCT05355883?
This trial is currently completed. It is a NA study. The enrollment target is 51 participants. The study started on 2021-12-18. Estimated completion is 2025-05-30.
What interventions are being tested in trial NCT05355883?
The interventions under investigation include: Sham conditioning (BEHAVIORAL), Balance training (BEHAVIORAL), Remote Ischemic Conditioning (RIC) (BEHAVIORAL), Hand Arm Bimanual Intensive Therapy (HABIT) (BEHAVIORAL), Bimanual Cup Stacking Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT05355883?
This trial is sponsored by East Carolina University, which has 58 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05355883's enrollment target sits among peer trials
51 1279th of 2000 higher than 722 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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