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NCT05347446 · ClinicalTrials.gov registry record · NA
Hybrid Versus Non-Hybrid Endoscopic Submucosal Dissection for Colorectal Polyps (SHORT-ESD)
A NA study, sponsored by AdventHealth.
- Completed
- Registry status
- NA
- Development phase
- 247
- Enrollment target
NCT05347446: Completed NA study, sponsored by AdventHealth.
NCT05347446 is a NA study that has completed, run by AdventHealth. The registered enrollment target is 247 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05347446, a NA study, has completed, sponsored by AdventHealth.
- COMPLETED
- Registry status
- NA
- Development phase
- 247 participants
- Enrollment target
Study Summary
This proposed trial will randomize 60 patients with a ≥20 mm large colorectal polyp to either undergo hybrid or non-hybrid ESD. For the primary comparison (hybrid vs non-hybrid ESD), the primary outcome will be procedure time. The study will further examine the safety and efficacy of hybrid ESD compared to non-hybrid ESD and investigate factors that may be associated with resection outcomes.
Primary Outcome
The primary endpoint is to compare procedural time between hybrid vs non-hybrid ESD. Procedure time is defined as the time from the beginning of the submucosal injection to completion of the ESD, defined as complete removal of the polyp from the colonic wall and all interventions for any intraprocedural adverse events. Procedure speed will be calculated by diving the area of the resected specimen by the procedure time (cm2/minute). The following formula will be used to calculate the area: π (3.
Interventions
- PROCEDURE Hybrid ESD
- PROCEDURE Non-hybrid ESD
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 247 participants |
| Start Date | 2022-05-09 |
| Est. Completion | 2024-12-19 |
| Phase | NA |
What the finished NCT05347446 record still lists
NCT05347446 is an interventional study that assigns participants to a tested intervention. The registered 247 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 2 interventions - of which Hybrid ESD is the first listed.
NCT05347446 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05347446 about?
NCT05347446 is a clinical study titled "Hybrid Versus Non-Hybrid Endoscopic Submucosal Dissection for Colorectal Polyps (SHORT-ESD)". This proposed trial will randomize 60 patients with a ≥20 mm large colorectal polyp to either undergo hybrid or non-hybrid ESD. For the primary comparison (hybrid vs non-hybrid ESD), the primary outcome will be procedure time. The study will further examine the safety and efficacy of hybrid ESD comp...
What is the current status of trial NCT05347446?
This trial is currently completed. It is a NA study. The enrollment target is 247 participants. The study started on 2022-05-09. Estimated completion is 2024-12-19.
What interventions are being tested in trial NCT05347446?
The interventions under investigation include: Hybrid ESD (PROCEDURE), Non-hybrid ESD (PROCEDURE).
Who is sponsoring clinical trial NCT05347446?
This trial is sponsored by AdventHealth, which has 95 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05347446's enrollment target sits among peer trials
247 436th of 2000 higher than 1,565 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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