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NCT05316519 · ClinicalTrials.gov registry record · NA
Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning
A NA study, sponsored by VA Pittsburgh Healthcare System.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT05316519: Clinical Trial NA study, sponsored by VA Pittsburgh Healthcare System.
NCT05316519 is a NA study that was terminated before completion, run by VA Pittsburgh Healthcare System. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05316519, a NA study, was terminated before completion, sponsored by VA Pittsburgh Healthcare System.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Vagus nerve stimulation (VNS) activates neural pathways leading to the release of chemicals that promote plasticity and learning. Previous work has shown that the auricular branch of the vagus nerve innervates landmarks on the external ear. Work from the PI's laboratory has shown that electrical current applied to the external ear activates neural pathways implicated in the therapeutic effects of VNS. The broad objective of this project is to better understand physiological mechanisms that are modulated by auricular stimulation and its potential to enhance motor learning.
Primary Outcome
The ability to stabilize precision grip according to target force and/or preload force will be quantified by calculating coefficient of variation (CV) or root-mean-square error (RMSE) which characterize variability in relation to mean force or target force.
Interventions
- OTHER Transcutaneous Vagus Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2023-12-31 |
| Phase | NA |
Why NCT05316519 stopped before completion
NCT05316519 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Transcutaneous Vagus Nerve Stimulation is the first listed.
NCT05316519 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05316519 about?
NCT05316519 is a clinical study titled "Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning". Vagus nerve stimulation (VNS) activates neural pathways leading to the release of chemicals that promote plasticity and learning. Previous work has shown that the auricular branch of the vagus nerve innervates landmarks on the external ear. Work from the PI's laboratory has shown that electrical cur...
What is the current status of trial NCT05316519?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2022-06-01. Estimated completion is 2023-12-31.
What interventions are being tested in trial NCT05316519?
The interventions under investigation include: Transcutaneous Vagus Nerve Stimulation (OTHER).
Who is sponsoring clinical trial NCT05316519?
This trial is sponsored by VA Pittsburgh Healthcare System, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05316519's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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