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NCT05316272 · ClinicalTrials.gov registry record · NA
Effects of DHEA and Exercise on Bone Marrow Fat in Postmenopausal Women
A NA study, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- NA
- Development phase
- 41
- Enrollment target
NCT05316272: Completed NA study, sponsored by University of Colorado, Denver.
NCT05316272 is a NA study that has completed, run by University of Colorado, Denver. The registered enrollment target is 41 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05316272, a NA study, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- NA
- Development phase
- 41 participants
- Enrollment target
Study Summary
Bone strength -the main determinant of bone fracture- is a function not only of bone mineral density (BMD) and microstructure, but also of its microenvironment, including bone marrow fat (BMF). The adrenal steroid dehydroepiandrosterone (DHEA) -the main precursor for estrogens and androgens in postmenopausal women- as well as bone-loading exercise, increase BMD in older women, however, their effects on BMF are largely unknown. This study has high potential to unveil the hormonal and mechanical effects of DHEA and exercise on BMF, respectively, and to elucidate longitudinal associations of BMF with bone strength in older women with bone loss.
Primary Outcome
changes in bone marrow fat content of the lumbar spine
Interventions
- BEHAVIORAL Exercise
- DIETARY_SUPPLEMENT DHEA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2022-03-11 |
| Est. Completion | 2024-06-30 |
| Phase | NA |
What the finished NCT05316272 record still lists
NCT05316272 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Exercise is the first listed.
NCT05316272 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05316272 about?
NCT05316272 is a clinical study titled "Effects of DHEA and Exercise on Bone Marrow Fat in Postmenopausal Women". Bone strength -the main determinant of bone fracture- is a function not only of bone mineral density (BMD) and microstructure, but also of its microenvironment, including bone marrow fat (BMF). The adrenal steroid dehydroepiandrosterone (DHEA) -the main precursor for estrogens and androgens in postm...
What is the current status of trial NCT05316272?
This trial is currently completed. It is a NA study. The enrollment target is 41 participants. The study started on 2022-03-11. Estimated completion is 2024-06-30.
What interventions are being tested in trial NCT05316272?
The interventions under investigation include: Exercise (BEHAVIORAL), DHEA (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05316272?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05316272's enrollment target sits among peer trials
41 1446th of 2000 higher than 554 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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