Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05313152 · ClinicalTrials.gov registry record · Phase 1

Study of TAVO103A in Healthy Volunteers

A Phase 1 study, sponsored by Tavotek Biotherapeutics.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT05313152: Completed Phase 1 study, sponsored by Tavotek Biotherapeutics.

NCT05313152 is a Phase 1 study that has completed, run by Tavotek Biotherapeutics. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT05313152, a Phase 1 study, has completed, sponsored by Tavotek Biotherapeutics.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

This is a Phase 1, single ascending dose study designed to investigate TAVO103A, administered as an IV infusion up to 60 minutes in length to healthy adult subjects. This study is designed to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAVO103A.

Primary Outcome

To investigate the safety and tolerability of TAVO103A in healthy volunteers. The Toxicity Grading Scale for Healthy Adult and Adolescent Volunteers Enrolled in Preventive Vaccine Clinical Trials will be graded according to the National Cancer Institute's Common Terminology Criteria for AEs, Version 5.0. Which will have a minimum value of Grade 1, or mild, and a maximum value of Grade 4, or Potentially Life Threatening.

Interventions

  • OTHER Placebo
  • DRUG TAVO103A

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2022-04-05
Est. Completion 2023-06-08
Phase Phase 1
Tavotek Biotherapeutics

2 total trials

What the finished NCT05313152 record still lists

NCT05313152 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05313152 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05313152 about?

NCT05313152 is a clinical study titled "Study of TAVO103A in Healthy Volunteers". This is a Phase 1, single ascending dose study designed to investigate TAVO103A, administered as an IV infusion up to 60 minutes in length to healthy adult subjects. This study is designed to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAVO103A.

What is the current status of trial NCT05313152?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2022-04-05. Estimated completion is 2023-06-08.

What interventions are being tested in trial NCT05313152?

The interventions under investigation include: Placebo (OTHER), TAVO103A (DRUG).

Who is sponsoring clinical trial NCT05313152?

This trial is sponsored by Tavotek Biotherapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05313152's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05313152, the US trial registry maintained by the National Library of Medicine. NCT05313152 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.