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NCT05300685 · ClinicalTrials.gov registry record · Phase 3
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
A Phase 3 study of Urethral Stricture, Male, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 60
- Enrollment target
- 2
- Study locations
NCT05300685 is a Phase 3 study of Urethral Stricture, Male that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 60 participants. The trial reports 2 study locations across 2 states.
The verdict
NCT05300685, a Phase 3 study of Urethral Stricture, Male, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 60 participants
- Enrollment target
- 2
- Study locations
Study Summary
Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this patient population. In addition to traditional post operative pain control, groups have sought various peri-operative anesthetic regimens to improve post operative pain. This has led recently to the description of various regional blocks including buccal and periorbital blocks for peri-operative local anesthetic. No study has looked at superiority of regional pain management in this patient population. This study will aim to assess three established anesthetic protocols for oral pain control in a blinded, randomized controlled trial. Hypothesis: Patients who have buccal block will have lower post op pain without any increase adverse oral outcomes.
Conditions Studied
Interventions
- DRUG Standard Buccal Harvest
- DRUG Basic buccal procedure + Long acting local
- DRUG Basic buccal procedure + Buccal block
Study Locations (2)
California
- University of California San Francisco - San Francisco
District of Columbia
- MedStar Urology - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-02-15 |
| Est. Completion | 2026-03-01 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05300685
The ClinicalTrials.gov registry entry for NCT05300685 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Urethral Stricture, Male appearing as the primary indexed condition, and to 3 interventions - of which Standard Buccal Harvest is the first listed.
NCT05300685 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, District of Columbia.
Frequently Asked Questions
What is clinical trial NCT05300685 about?
NCT05300685 is a clinical study titled "Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty". Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no est...
What is the current status of trial NCT05300685?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2022-02-15. Estimated completion is 2026-03-01.
What conditions does trial NCT05300685 study?
This clinical trial studies the following conditions: Urethral Stricture, Male.
What interventions are being tested in trial NCT05300685?
The interventions under investigation include: Standard Buccal Harvest (DRUG), Basic buccal procedure + Long acting local (DRUG), Basic buccal procedure + Buccal block (DRUG).
Who is sponsoring clinical trial NCT05300685?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05300685 being conducted?
This trial has 2 study locations across California, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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