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NCT05281198 · ClinicalTrials.gov registry record · NA
Effects of Exercise & Tart Cherry Ingestion on Heat Acclimation and Gut Microbiome
A NA study, sponsored by Ohio University.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT05281198: Clinical Trial NA study, sponsored by Ohio University.
NCT05281198 is a NA study that was terminated before completion, run by Ohio University. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05281198, a NA study, was terminated before completion, sponsored by Ohio University.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether tart cherry supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determine if tart cherry in combination with repeated bouts of thermally stressful exercise will impact the gut microbiome \& inflammation measured via stool sample \& blood samples for plasma endotoxin, inflammatory cytokines and HSP. Specific Aim II. To determine whether whole body hyperthermia causes changes in bacterial populations in the gut microbiome, and if these changes are affected by washout or re-acclimation. Specific Aim III. To determine whether tart cherry supplementation suppresses the ability of human subjects to acclimate to exercise/heat stress. This will be assessed via body temperature, heart rate, sweat and plasma volume responses, and exercise performance during standardized heat tolerance tests.
Primary Outcome
Plasma TNF-a changes from pre to 1 hour post heat tolerance test
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT tart cherry juice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2022-01-26 |
| Est. Completion | 2023-04-30 |
| Phase | NA |
Why NCT05281198 stopped before completion
NCT05281198 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05281198 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05281198 about?
NCT05281198 is a clinical study titled "Effects of Exercise & Tart Cherry Ingestion on Heat Acclimation and Gut Microbiome". The purpose of this study is to determine whether tart cherry supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determine if tart cherry in combination with repeated bouts of thermally stressful exercise will impact th...
What is the current status of trial NCT05281198?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2022-01-26. Estimated completion is 2023-04-30.
What interventions are being tested in trial NCT05281198?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), tart cherry juice (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05281198?
This trial is sponsored by Ohio University, which has 51 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05281198's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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