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RECRUITING Phase 1

A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas

NCT05279300 · View on ClinicalTrials.gov ↗

Study Summary

This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug CS5001 used as a single agent and in combination with systemic therapies in patients with advanced hematological and solid tumors.

Interventions

  • DRUG Oxaliplatin
  • DRUG Lenalidomide
  • DRUG Gemcitabine
  • BIOLOGICAL Rituximab
  • DRUG CS5001

Study Locations (20)

South Australia

  • Ashford Cancer Centre Research — Adelaide
  • Central Adelaide Local Health Network Incorporated — Adelaide
  • Royal Adelaide Hospital (RAH) — Adelaide

Beijing Municipality

  • Beijing Cancer Hospital — Beijing
  • Beijing Cancer Hospital — Beijing
  • Yanda Lu Dao Pei Hospital — Beijing

New York

  • North Shore Hematology Oncology Associates — East Setauket
  • Columbia U. - Herbert Irving Comprehensive Cancer Center — New York

Victoria

  • Epworth Freemasons Medical Centre — East Melbourne
  • Epworth Foundation trading as Epworth HealthCare — Melbourne

Anhui

  • Anhui Provincial Cancer Hospital — Hefei
  • Anhui Provincial Hospital, — Hefei

Guangdong

  • Guangdong Province Hospital — Guangzhou
  • Sun YatSen University Cancer Center — Guangzhou

Texas

  • BUMC - Mary Crowley Cancer Research Centers (MCCRC) — Dallas

New South Wales

  • Scientia Clinical Research Limited — Randwick

Trial Details

FieldValue
Enrollment Target 480 participants
Start Date 2022-03-28
Est. Completion 2027-12-31
Phase Phase 1

Sponsor

CStone Pharmaceuticals

30 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05279300

The ClinicalTrials.gov registry entry for NCT05279300 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 480 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is CStone Pharmaceuticals, which has 30 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Advanced Solid Tumor appearing as the primary indexed condition, and to 5 interventions — of which Oxaliplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05279300 reports 20 study locations spanning 12 distinct geographic areas — top geographies include South Australia, Beijing Municipality, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05279300 about?

NCT05279300 is a clinical study titled "A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas". This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug CS5001 used as a single agent and in combination with systemic therapies in patients with advanced hematological and solid tumors.

What is the current status of trial NCT05279300?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 480 participants. The study started on 2022-03-28. Estimated completion is 2027-12-31.

What conditions does trial NCT05279300 study?

This clinical trial studies the following conditions: Advanced Solid Tumor, Advanced Lymphoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05279300?

The interventions under investigation include: Oxaliplatin (DRUG), Lenalidomide (DRUG), Gemcitabine (DRUG), Rituximab (BIOLOGICAL), CS5001 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05279300?

This trial is sponsored by CStone Pharmaceuticals, which has 30 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05279300 being conducted?

This trial has 20 study locations across New York, Texas, New South Wales, South Australia, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial