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NCT05277896 · ClinicalTrials.gov registry record · Phase 4
Randomized Trial of Sedative Choice for Intubation
A Phase 4 study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 2,367
- Enrollment target
NCT05277896 is a Phase 4 study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 2,367 participants.
The verdict
NCT05277896, a Phase 4 study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 2,367 participants
- Enrollment target
Study Summary
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains unknown. Ketamine and etomidate are the two most commonly used sedatives during intubation of critically ill adults. Data from a randomized clinical trial are urgently needed to determine the effect of ketamine versus etomidate on cardiovascular complications and clinical outcomes of emergency tracheal intubation.
Interventions
- DRUG Ketamine
- DRUG Etomidate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,367 participants |
| Start Date | 2022-04-06 |
| Est. Completion | 2025-09-06 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05277896
The ClinicalTrials.gov registry entry for NCT05277896 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 2,367 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Ketamine is the first listed.
NCT05277896 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05277896 about?
NCT05277896 is a clinical study titled "Randomized Trial of Sedative Choice for Intubation". Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, bu...
What is the current status of trial NCT05277896?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 2,367 participants. The study started on 2022-04-06. Estimated completion is 2025-09-06.
What interventions are being tested in trial NCT05277896?
The interventions under investigation include: Ketamine (DRUG), Etomidate (DRUG).
Who is sponsoring clinical trial NCT05277896?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
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