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NCT05271604 · ClinicalTrials.gov registry record · Phase 2
A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
A Phase 2 study, sponsored by BioAtla.
- Completed
- Registry status
- Phase 2
- Development phase
- 42
- Enrollment target
NCT05271604: Completed Phase 2 study, sponsored by BioAtla.
NCT05271604 is a Phase 2 study that has completed, run by BioAtla. The registered enrollment target is 42 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05271604, a Phase 2 study, has completed, sponsored by BioAtla.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 42 participants
- Enrollment target
Study Summary
This is a multi-center, open-label Phase 2 study designed to evaluate the efficacy and safety of BA3021 as monotherapy and combination therapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.
Primary Outcome
Proportion of patients who achieve a confirmed CR or PR according to RECIST v1.1
Interventions
- BIOLOGICAL Pembrolizumab
- BIOLOGICAL Cetuximab
- BIOLOGICAL Ozuriftamab Vedotin
- BIOLOGICAL Evalstotug (BA3071)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2022-12-13 |
| Est. Completion | 2025-09-22 |
| Phase | Phase 2 |
What the finished NCT05271604 record still lists
NCT05271604 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 4 interventions - of which Pembrolizumab is the first listed.
NCT05271604 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05271604 about?
NCT05271604 is a clinical study titled "A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck". This is a multi-center, open-label Phase 2 study designed to evaluate the efficacy and safety of BA3021 as monotherapy and combination therapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.
What is the current status of trial NCT05271604?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2022-12-13. Estimated completion is 2025-09-22.
What interventions are being tested in trial NCT05271604?
The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Cetuximab (BIOLOGICAL), Ozuriftamab Vedotin (BIOLOGICAL), Evalstotug (BA3071) (BIOLOGICAL).
Who is sponsoring clinical trial NCT05271604?
This trial is sponsored by BioAtla, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05271604's enrollment target sits among peer trials
42 1339th of 2000 higher than 649 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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