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NCT05267652 · ClinicalTrials.gov registry record · NA
Pragmatic Trial Examining Oxygenation Prior to Intubation
A NA study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 1,301
- Enrollment target
NCT05267652: Completed NA study, sponsored by Vanderbilt University Medical Center.
NCT05267652 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 1,301 participants, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05267652, a NA study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,301 participants
- Enrollment target
Study Summary
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk of life-threatening hypoxemia. In current clinical practice, the most common methods for preoxygenation are non-invasive positive pressure ventilation and facemask oxygen. Prior trials comparing non-invasive positive pressure ventilation and facemask oxygen for preoxygenation have been small and have yielded conflicting results. A better understanding of the comparative effectiveness of these two common, standard-of-care approaches to preoxygenation could improve the care clinicians deliver and patient outcomes.
Primary Outcome
A peripheral oxygen saturation \< 85% during the interval between induction and 2 minutes after tracheal intubation
Interventions
- OTHER Preoxygenation with Non-Invasive Positive Pressure Ventilation
- OTHER Facemask Oxygen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,301 participants |
| Start Date | 2022-03-10 |
| Est. Completion | 2023-11-11 |
| Phase | NA |
What the finished NCT05267652 record still lists
NCT05267652 is an interventional study that assigns participants to a tested intervention. Its 1,301 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Preoxygenation with Non-Invasive Positive Pressure Ventilation is the first listed.
NCT05267652 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05267652 about?
NCT05267652 is a clinical study titled "Pragmatic Trial Examining Oxygenation Prior to Intubation". Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplement...
What is the current status of trial NCT05267652?
This trial is currently completed. It is a NA study. The enrollment target is 1,301 participants. The study started on 2022-03-10. Estimated completion is 2023-11-11.
What interventions are being tested in trial NCT05267652?
The interventions under investigation include: Preoxygenation with Non-Invasive Positive Pressure Ventilation (OTHER), Facemask Oxygen (OTHER).
Who is sponsoring clinical trial NCT05267652?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05267652's enrollment target sits among peer trials
1,301 76th of 2000 higher than 1,925 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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