Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05262361 · ClinicalTrials.gov registry record · NA

Persistent Post-Concussion Symptoms With Convergence Insufficiency

A NA study, sponsored by New Jersey Institute of Technology.

Completed
Registry status
NA
Development phase
112
Enrollment target

NCT05262361: Completed NA study, sponsored by New Jersey Institute of Technology.

NCT05262361 is a NA study that has completed, run by New Jersey Institute of Technology. The registered enrollment target is 112 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05262361, a NA study, has completed, sponsored by New Jersey Institute of Technology.

COMPLETED
Registry status
NA
Development phase
112 participants
Enrollment target

Study Summary

Our successful R01 discovered 1) the neural mechanistic difference between typically occurring convergence insufficiency (TYP-CI) and binocularly normal controls and 2) the underlying mechanism of office-based vergence and accommodative therapy (OBVAT) that is effective in remediating symptoms. Adolescent and young adult concussion is considered a substantial health problem in the United States where our team has shown that about half of patients with persistent post-concussion symptoms have convergence insufficiency (PPCS-CI), causing significant negative impact associated with reading or digital screen-related activities, and is believed to be one factor causing delayed recovery impacting return to school, sports, or work. The results of this randomized clinical trial will impact the lives of adolescents and young adults with PPCS-CI to guide professionals on how to manage and treat those with PPCS-CI by 1) comparing the differences between PPCS-CI and TYP-CI, 2) discovering the neural mechanism of OBVAT for PPCS-CI compared to standard-community concussion care, and 3) determining the effectiveness of 12 one-hour sessions compared to 16 one-hour sessions of OBVAT.

Primary Outcome

Composite score of how close a participant can view a target a single along midline combined with positive fusional vergence range.

Interventions

  • BEHAVIORAL Office-based Vergence and Accommodative Therapy

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 2021-09-01
Est. Completion 2026-01-19
Phase NA

What the finished NCT05262361 record still lists

NCT05262361 is an interventional study that assigns participants to a tested intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Office-based Vergence and Accommodative Therapy is the first listed.

NCT05262361 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05262361 about?

NCT05262361 is a clinical study titled "Persistent Post-Concussion Symptoms With Convergence Insufficiency". Our successful R01 discovered 1) the neural mechanistic difference between typically occurring convergence insufficiency (TYP-CI) and binocularly normal controls and 2) the underlying mechanism of office-based vergence and accommodative therapy (OBVAT) that is effective in remediating symptoms. Adol...

What is the current status of trial NCT05262361?

This trial is currently completed. It is a NA study. The enrollment target is 112 participants. The study started on 2021-09-01. Estimated completion is 2026-01-19.

What interventions are being tested in trial NCT05262361?

The interventions under investigation include: Office-based Vergence and Accommodative Therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT05262361?

This trial is sponsored by New Jersey Institute of Technology, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05262361's enrollment target sits among peer trials

112 813th of 2000 higher than 1,185 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04511013 · 112 participants · Phase 2

    A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

  • NCT04551560 · 112 participants · NA

    Stress and Congestive Heart Failure

  • NCT04872166 · 112 participants · Phase 1

    A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

  • NCT05024773 · 112 participants · Phase 3

    Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05262361, the US trial registry maintained by the National Library of Medicine. NCT05262361 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.