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NCT05257941 · ClinicalTrials.gov registry record · Phase 1
ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery
A Phase 1 study, sponsored by Indiana University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 116
- Enrollment target
NCT05257941: Clinical Trial Phase 1 study, sponsored by Indiana University.
NCT05257941 is a Phase 1 study that was terminated before completion, run by Indiana University. The registered enrollment target is 116 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05257941, a Phase 1 study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 116 participants
- Enrollment target
Study Summary
This study is being done to compare 2 types of pain control methods and determine which is more effective postoperatively for laparoscopic colorectal surgery. Group 1 will receive an intrathecal (IT) injection in the back in which a small dose duramorph and bupivacaine will be placed into the spinal fluid. Group 2 will receive an erector spinae plane (ESP) block in which bupivacaine and decadron are injected near the nerves under a muscle in the back.
Primary Outcome
24 hour cumulated oral morphine consumption (OME)
Interventions
- DRUG IT Injection
- DRUG ESP Block
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2022-01-27 |
| Est. Completion | 2024-08-29 |
| Phase | Phase 1 |
Why NCT05257941 stopped before completion
NCT05257941 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% higher).
The record links to 0 conditions, and to 2 interventions - of which IT Injection is the first listed.
NCT05257941 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05257941 about?
NCT05257941 is a clinical study titled "ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery". This study is being done to compare 2 types of pain control methods and determine which is more effective postoperatively for laparoscopic colorectal surgery. Group 1 will receive an intrathecal (IT) injection in the back in which a small dose duramorph and bupivacaine will be placed into the spinal...
What is the current status of trial NCT05257941?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 116 participants. The study started on 2022-01-27. Estimated completion is 2024-08-29.
What interventions are being tested in trial NCT05257941?
The interventions under investigation include: IT Injection (DRUG), ESP Block (DRUG).
Who is sponsoring clinical trial NCT05257941?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05257941's enrollment target sits among peer trials
116 501st of 2000 higher than 1,497 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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