Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 3

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

NCT05257408 · View on ClinicalTrials.gov ↗

Study Summary

The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated with intermittent regimen of Relacorilant in combination with nab-paclitaxel compared with patients treated with nab-paclitaxel monotherapy.

Interventions

  • DRUG Relacorilant 150 mg once daily (QD)
  • DRUG Nab-paclitaxel 80 mg/m^2
  • DRUG Nab-paclitaxel 100 mg/m^2

Study Locations (20)

California

  • Site 350 — Irvine
  • Site 364 — La Jolla
  • Site 150 — Palo Alto
  • Site 278 — San Francisco
  • Site 014 — San Francisco
  • Site 316 — Solvang

Georgia

  • Site 009 — Atlanta
  • Site 272 — Atlanta
  • Site 372 — Gainesville
  • Site 291 — Savannah

Illinois

  • Site 315 — Evanston
  • Site 314 — Hinsdale
  • Site 346 — Urbana

Arizona

  • Site 318 — Phoenix
  • Site 277 — Tucson

Florida

  • Site 335 — Miami Beach
  • Site 042 — Weston

Colorado

  • Site 032 — Aurora

Indiana

  • Site 339 — Indianapolis

Kansas

  • Site 200 — Overland Park

Trial Details

FieldValue
Enrollment Target 381 participants
Start Date 2022-06-29
Est. Completion 2026-03
Phase Phase 3

Sponsor

Corcept Therapeutics

15 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05257408

The ClinicalTrials.gov registry entry for NCT05257408 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 381 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Corcept Therapeutics, which has 15 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Peritoneal Neoplasms appearing as the primary indexed condition, and to 3 interventions — of which Relacorilant 150 mg once daily (QD) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05257408 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Georgia, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05257408 about?

NCT05257408 is a clinical study titled "Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer". The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated with intermittent regimen of Relacorilant in combination with nab-pacli...

What is the current status of trial NCT05257408?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 381 participants. The study started on 2022-06-29. Estimated completion is 2026-03.

What conditions does trial NCT05257408 study?

This clinical trial studies the following conditions: Peritoneal Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasm. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05257408?

The interventions under investigation include: Relacorilant 150 mg once daily (QD) (DRUG), Nab-paclitaxel 80 mg/m^2 (DRUG), Nab-paclitaxel 100 mg/m^2 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05257408?

This trial is sponsored by Corcept Therapeutics, which has 15 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05257408 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial