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NCT05255484 · ClinicalTrials.gov registry record · Phase 1
Study of LM-108 as a Single Agent or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumours
A Phase 1 study, sponsored by LaNova Medicines Limited.
- Terminated
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT05255484: Clinical Trial Phase 1 study, sponsored by LaNova Medicines Limited.
NCT05255484 is a Phase 1 study that was terminated before completion, run by LaNova Medicines Limited. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05255484, a Phase 1 study, was terminated before completion, sponsored by LaNova Medicines Limited.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
A Phase I/II, Open-Label, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of LM-108 as a Single Agent or in Combination with Pembrolizumab in Advanced Solid Tumors
Primary Outcome
Incidence of adverse events
Interventions
- DRUG LM-108
- DRUG An Anti-PD-1 Antibody
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2022-05-26 |
| Est. Completion | 2023-10-06 |
| Phase | Phase 1 |
Why NCT05255484 stopped before completion
NCT05255484 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which LM-108 is the first listed.
NCT05255484 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05255484 about?
NCT05255484 is a clinical study titled "Study of LM-108 as a Single Agent or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumours". A Phase I/II, Open-Label, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of LM-108 as a Single Agent or in Combination with Pembrolizumab in Advanced Solid Tumors
What is the current status of trial NCT05255484?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2022-05-26. Estimated completion is 2023-10-06.
What interventions are being tested in trial NCT05255484?
The interventions under investigation include: LM-108 (DRUG), An Anti-PD-1 Antibody (DRUG).
Who is sponsoring clinical trial NCT05255484?
This trial is sponsored by LaNova Medicines Limited, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05255484's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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