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NCT05254080 · ClinicalTrials.gov registry record · NA
taVNS Cold Pressor
A NA study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT05254080: Completed NA study, sponsored by Medical University of South Carolina.
NCT05254080 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05254080, a NA study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study explores the use of transcutaneous auricular vagus nerve stimulation (taVNS), a new form of neuromodulation which stimulates the ear. 24 healthy subjects without a past medical or psychiatric history will be recruited to participate in a phone screen followed by 1 lab visit. During the lab visit, subjects will participate twice in a validated stress induction technique called the cold pressor test, while concurrently receiving either active or sham taVNS. The cold pressor test consists of subjects placing their feet in an ice bath for a short period of time. Researchers will measure participant's heart rate while they receive taVNS (ear stimulation) and participate in the cold pressor test. Assessments of mood, anxiety, and stress will be collected at the beginning and end of the visit.
Primary Outcome
Heart rate will be measured with EKG electrodes before concurrent stress test and ear stimulation.
Interventions
- DEVICE Sham taVNS
- DEVICE Active taVNS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-10-01 |
| Est. Completion | 2021-12-20 |
| Phase | NA |
What the finished NCT05254080 record still lists
NCT05254080 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham taVNS is the first listed.
NCT05254080 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05254080 about?
NCT05254080 is a clinical study titled "taVNS Cold Pressor". This study explores the use of transcutaneous auricular vagus nerve stimulation (taVNS), a new form of neuromodulation which stimulates the ear. 24 healthy subjects without a past medical or psychiatric history will be recruited to participate in a phone screen followed by 1 lab visit. During the la...
What is the current status of trial NCT05254080?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2021-10-01. Estimated completion is 2021-12-20.
What interventions are being tested in trial NCT05254080?
The interventions under investigation include: Sham taVNS (DEVICE), Active taVNS (DEVICE).
Who is sponsoring clinical trial NCT05254080?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05254080's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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