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NCT05243914 · ClinicalTrials.gov registry record
Heart Transplantation Utilizing NRP DCD
A clinical trial, sponsored by University of Arizona.
- Terminated
- Registry status
- 56
- Enrollment target
NCT05243914: Clinical Trial study, sponsored by University of Arizona.
NCT05243914 is a clinical trial that was terminated before completion, run by University of Arizona. The registered enrollment target is 56 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05243914 was terminated before completion, sponsored by University of Arizona.
- TERMINATED
- Registry status
- 56 participants
- Enrollment target
Study Summary
This is a prospective, observational, pilot trial to evaluate the feasibility of heart transplantation using normothermic regional perfusion (NRP) donation after donor circulatory death (DCD). Adults who meet standard criteria for heart transplantation listing and study-specific eligibility criteria will enroll in the study. the investigators anticipate evaluating an initial cohort of approximately 100 DCD donors for a final yield of 40 hearts. The investigators will accept donors between the ages of 18 and 65 who are determined to have heart function/quality appropriate for donation for transplantation based on available donor data and testing. If feasible, donors might be relocated to BUMCP to maintain uniformity of process, minimize cold ischemic time, and allow for more rapid and improved communication during the initial pilot phase. Recipients will be selected based on blood group, crossmatch, size match, and clinical stability per standard allocation practices. Recipients will be followed post-transplantation per BUMCP Heart Transplant standard protocol.
Primary Outcome
To evaluate the survival of heart transplantation recipients using normothermic regional perfusion (NRP) donation after circulatory death (DCD).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2022-01-21 |
| Est. Completion | 2024-01-03 |
Why NCT05243914 stopped before completion
NCT05243914 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT05243914 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05243914 about?
NCT05243914 is a clinical study titled "Heart Transplantation Utilizing NRP DCD". This is a prospective, observational, pilot trial to evaluate the feasibility of heart transplantation using normothermic regional perfusion (NRP) donation after donor circulatory death (DCD). Adults who meet standard criteria for heart transplantation listing and study-specific eligibility criteria...
What is the current status of trial NCT05243914?
This trial is currently terminated. The enrollment target is 56 participants. The study started on 2022-01-21. Estimated completion is 2024-01-03.
Who is sponsoring clinical trial NCT05243914?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
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