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NCT05242900 · ClinicalTrials.gov registry record
Imaging Sodium and Lymphatics in Lymphedema
A clinical trial of Lymphedema, Secondary and Lymphedema of Leg, sponsored by University of Virginia.
- Active
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT05242900: Active study of Lymphedema, Secondary and Lymphedema of Leg, sponsored by University of Virginia.
NCT05242900 is a study of Lymphedema, Secondary and Lymphedema of Leg that is active but no longer recruiting, run by University of Virginia. The registered enrollment target is 75 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05242900, a study of Lymphedema, Secondary and Lymphedema of Leg, is active but no longer recruiting, sponsored by University of Virginia.
- ACTIVE NOT RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
Recent evidence supports lymphatic regulation of tissue sodium handling, however fundamental gaps persist in knowledge regarding the role of lymphatics in human diseases of sodium dysregulation. The goal of this work is to apply novel, noninvasive imaging tools to measure relationships between lymphatic function and tissue sodium in patients with well-characterized lymphedema. Findings are intended to inform mechanisms of lymphatic clearance of tissue sodium, and provide novel imaging biomarkers of lymphedema progression and treatment response.
Primary Outcome
Research participants will undergo periodic noninvasive sodium MRI after clinically-indicated complete decongestive therapy. The study team will measure change in tissue sodium content (mmol/L) in the treated extremities to study effects of lymphatic stimulation on sodium clearance.
Conditions Studied
Interventions
- PROCEDURE Complete decongestive therapy
- OTHER Standard imaging protocol
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2021-10-10 |
| Est. Completion | 2025-12 |
What the registry record for NCT05242900 still lists
NCT05242900 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target.
The record links to 3 conditions, with Lymphedema, Secondary appearing as the primary indexed condition, and to 2 interventions - of which Complete decongestive therapy is the first listed.
NCT05242900 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT05242900 about?
NCT05242900 is a clinical study titled "Imaging Sodium and Lymphatics in Lymphedema". Recent evidence supports lymphatic regulation of tissue sodium handling, however fundamental gaps persist in knowledge regarding the role of lymphatics in human diseases of sodium dysregulation. The goal of this work is to apply novel, noninvasive imaging tools to measure relationships between lymph...
What is the current status of trial NCT05242900?
This trial is currently active not recruiting. The enrollment target is 75 participants. The study started on 2021-10-10. Estimated completion is 2025-12.
What conditions does trial NCT05242900 study?
This clinical trial studies the following conditions: Lymphedema, Secondary, Lymphedema of Leg, Lymphedema Related Fibrosis.
What interventions are being tested in trial NCT05242900?
The interventions under investigation include: Complete decongestive therapy (PROCEDURE), Standard imaging protocol (OTHER).
Who is sponsoring clinical trial NCT05242900?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05242900 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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