Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05240014 · ClinicalTrials.gov registry record · NA
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses
A NA study of Lower-limb Orthoses and Frailty/Sarcopenia, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 33
- Enrollment target
- 1
- Study location
NCT05240014: Recruiting NA study of Lower-limb Orthoses and Frailty/Sarcopenia, sponsored by University of Michigan.
NCT05240014 is a NA study of Lower-limb Orthoses and Frailty/Sarcopenia that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 33 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05240014, a NA study of Lower-limb Orthoses and Frailty/Sarcopenia, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in broad patient populations. This project aims to establish feasibility of assisting different populations with these modular powered orthoses. The investigators hypothesize that assisting lower-limb musculature with modular powered orthoses will improve 1) lifting/lowering posture in able-bodied subjects and 2) functional outcomes in elderly subjects.
Primary Outcome
For each orthosis module tested, electromyography (EMG) readings will be normalized per-muscle by the peak EMG observed during the no-orthosis condition, and then averaged over the cycle and across repetitions to obtain "normalized exertion" values. Performance will be assessed by the difference between the orthosis condition and no-orthosis condition, averaging across tasks and muscles measured for the joint module.
Conditions Studied
Interventions
- DEVICE Modular powered orthosis
Study Locations (1)
Michigan
- Rehab Lab, University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2022-07-29 |
| Est. Completion | 2026-09-21 |
| Phase | NA |
What NCT05240014 shows while recruiting
NCT05240014 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Lower-limb Orthoses appearing as the primary indexed condition, and to 1 intervention - of which Modular powered orthosis is the first listed.
NCT05240014 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT05240014 about?
NCT05240014 is a clinical study titled "Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses". The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in broad patient populations. This project aims to establish feasibility of assisting different populatio...
What is the current status of trial NCT05240014?
This trial is currently recruiting. It is a NA study. The enrollment target is 33 participants. The study started on 2022-07-29. Estimated completion is 2026-09-21.
What conditions does trial NCT05240014 study?
This clinical trial studies the following conditions: Lower-limb Orthoses, Frailty/Sarcopenia, Chronic Overuse Musculoskeletal Injuries.
What interventions are being tested in trial NCT05240014?
The interventions under investigation include: Modular powered orthosis (DEVICE).
Who is sponsoring clinical trial NCT05240014?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05240014 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05240014's enrollment target sits among peer trials
33 1574th of 2000 higher than 423 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02861898 · 33 participants · Phase 1
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
- NCT04871607 · 33 participants · Phase 2
Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma
- NCT05071937 · 33 participants · Phase 2
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
- NCT05168618 · 33 participants · Phase 2
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI