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NCT05226780 · ClinicalTrials.gov registry record · Phase 2

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

A Phase 2 study of SCN8A Developmental and Epileptic Encephalopathy Syndrome, sponsored by Neurocrine Biosciences.

Active
Registry status
Phase 2
Development phase
8
Enrollment target
4
Study locations

NCT05226780 is a Phase 2 study of SCN8A Developmental and Epileptic Encephalopathy Syndrome that is active but no longer recruiting, run by Neurocrine Biosciences. The registered enrollment target is 8 participants. The trial reports 4 study locations across 4 states.

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The verdict

NCT05226780, a Phase 2 study of SCN8A Developmental and Epileptic Encephalopathy Syndrome, is active but no longer recruiting, sponsored by Neurocrine Biosciences.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
8 participants
Enrollment target
4
Study locations

Study Summary

Extension study to evaluate how safe and tolerable the drug NBI-921352 is when used as adjunctive therapy in participants with SCN8A developmental and epileptic encephalopathy syndrome (SCN8A-DEE).

Interventions

  • DRUG NBI-921352

Study Locations (4)

California

  • UCSF Medical Center - San Francisco

District of Columbia

  • Children's National Hospital - Washington D.C.

New York

  • University of Rochester - Rochester

Texas

  • Cook Children's Medical Center - Fort Worth

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2022-07-12
Est. Completion 2026-03
Phase Phase 2

Sponsor

Neurocrine Biosciences

65 total trials

What the Registry Record Tells You About NCT05226780

The ClinicalTrials.gov registry entry for NCT05226780 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Neurocrine Biosciences, which has 65 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with SCN8A Developmental and Epileptic Encephalopathy Syndrome appearing as the primary indexed condition, and to 1 intervention - of which NBI-921352 is the first listed.

NCT05226780 reports 4 study locations spanning 4 distinct geographic areas - top geographies include California, District of Columbia, New York.

Frequently Asked Questions

What is clinical trial NCT05226780 about?

NCT05226780 is a clinical study titled "Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE". Extension study to evaluate how safe and tolerable the drug NBI-921352 is when used as adjunctive therapy in participants with SCN8A developmental and epileptic encephalopathy syndrome (SCN8A-DEE).

What is the current status of trial NCT05226780?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2022-07-12. Estimated completion is 2026-03.

What conditions does trial NCT05226780 study?

This clinical trial studies the following conditions: SCN8A Developmental and Epileptic Encephalopathy Syndrome.

What interventions are being tested in trial NCT05226780?

The interventions under investigation include: NBI-921352 (DRUG).

Who is sponsoring clinical trial NCT05226780?

This trial is sponsored by Neurocrine Biosciences, which has 65 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05226780 being conducted?

This trial has 4 study locations across California, District of Columbia, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.