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A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
NCT05224102 · View on ClinicalTrials.gov ↗
Study Summary
This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino American, or Native American/Alaska Native/Native Hawaiian or other Pacific Islander; in addition, a cohort of Asian Indian participants will be enrolled in India.
Conditions Studied
Interventions
- DRUG Faricimab
Study Locations (20)
California
- Win Retina — Arcadia
- Retinal Diagnostic Center — Campbell
- Retina Consultants of Orange County — Fullerton
- Kaiser Permanente Southern California — Los Angeles
- Retinal Consultants Medical Group — Sacramento
Florida
- Blue Ocean Clinical Research — Clearwater
- Retina Macula Specialists of Miami - LeJeune Road Office — Miami
- Florida Retina Institute — Orlando
- Fort Lauderdale Eye Institute — Plantation
Maryland
- Wilmer Eye Institute Johns Hopkins University — Baltimore
- Md Medical Research — Oxon Hill
Nevada
- Retina Consultants of Nevada — Henderson
- Sierra Eye Associates — Reno
New Jersey
- The Retina Center of New Jersey — Bloomfield
- NJ Retina - Teaneck — Teaneck
Arizona
- Barnet Dulaney Perkins Eye Center — Phoenix
Colorado
- Southwest Retina Consultants — Durango
District of Columbia
- Emerson Clinical Research Institute LLC — Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 218 participants |
| Start Date | 2022-02-28 |
| Est. Completion | 2027-01-26 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05224102
The ClinicalTrials.gov registry entry for NCT05224102 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 218 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 206 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Diabetic Macular Edema appearing as the primary indexed condition, and to 1 intervention — of which Faricimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05224102 reports 20 study locations spanning 10 distinct geographic areas — top geographies include California, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05224102 about?
NCT05224102 is a clinical study titled "A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema". This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino Amer...
What is the current status of trial NCT05224102?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 218 participants. The study started on 2022-02-28. Estimated completion is 2027-01-26.
What conditions does trial NCT05224102 study?
This clinical trial studies the following conditions: Diabetic Macular Edema. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05224102?
The interventions under investigation include: Faricimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05224102?
This trial is sponsored by Genentech, which has 206 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05224102 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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