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NCT05224063 · ClinicalTrials.gov registry record · NA
Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT05224063: Completed NA study, sponsored by Stanford University.
NCT05224063 is a NA study that has completed, run by Stanford University. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05224063, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
Depression is a highly prevalent condition characterized by persistent low mood, energy, and activity that can affect one's thoughts, mood, behavior, and sense of well-being. Repetitive transcranial magnetic stimulation (rTMS), a non-invasive neuromodulatory technique, is an effective treatment for depression when targeting the dorsolateral prefrontal cortex (dlPFC) of the central executive network (CEN). However, remission rates are suboptimal and individual methods to target the dlPFC are lacking. In this study, we will enroll 50 patients with major depression and in a single rTMS 'dose,' prospective, randomized, double-blind, cross-over design will assess whether rTMS targeted to an individual's central executive network (CEN) assessed by single pulse TMS can enhance network modulation. If successful, this work will lead to a clinical rTMS trial comparing this personalized targeting approach against standard rTMS.
Interventions
- DEVICE Sham rTMS
- DEVICE Individualized CEN-targeted rTMS
- DEVICE Neuronavigated rTMS
- DEVICE Scalp-targeted rTMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2025-03-27 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05224063
The ClinicalTrials.gov registry entry for NCT05224063 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Sham rTMS is the first listed.
NCT05224063 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05224063 about?
NCT05224063 is a clinical study titled "Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression". Depression is a highly prevalent condition characterized by persistent low mood, energy, and activity that can affect one's thoughts, mood, behavior, and sense of well-being. Repetitive transcranial magnetic stimulation (rTMS), a non-invasive neuromodulatory technique, is an effective treatment for ...
What is the current status of trial NCT05224063?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2023-01-01. Estimated completion is 2025-03-27.
What interventions are being tested in trial NCT05224063?
The interventions under investigation include: Sham rTMS (DEVICE), Individualized CEN-targeted rTMS (DEVICE), Neuronavigated rTMS (DEVICE), Scalp-targeted rTMS (DEVICE).
Who is sponsoring clinical trial NCT05224063?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
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